Department of Surgery and Renal Transplant, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Saudi J Kidney Dis Transpl. 2021 Mar-Apr;32(2):510-521. doi: 10.4103/1319-2442.335464.
Live-related renal transplantation in India by "caregiver donors" provides huge financial, emotional, and physical support. Their psychological and mental health has not been addressed. We performed a prospective study using the World Health Organization Quality of Life (WHOQoL) BREF Scores and the Hospital Anxiety and Depression Scales preoperatively, at two weeks and three months after transplant. We included 30 pairs; most donors were females (80%, 60% mothers, 28% wives). The mean age of donors was 43.77 ± 10.64 years (34.8 ± 9.01 for recipients). There was improvement in the WHOQoL BREF after two weeks and three months as follows: physical domain (74.30 ± 9.74 vs. 78.30 ± 8.20; P = 0.001), and (74.30 ± 9.74 vs. 86.23 ± 7.25; P <0.001); psychological (74.90 ± 8.44 vs. 82.07 ± 7.19; P <0.001) and (74.90 ± 8.44 vs. 88.07 ± 6.89; P <0.001); environmental (75.33 ± 8.09 vs. 79.57 ± 6.18; P <0.001), and, (75.33 ± 8.09 vs. 86.97 ± 3.8; P <0.001); social-relationships (77.73 ± 8.28 vs. 79.77 ± 7.99; P <0.001), and (77.73 ± 8.28 vs. 84.77 ± 7.45; P <0.001). The recipient scores were similar. Factors with significant Pearson's or standardized beta co-efficient were donor age <20 years, donor complications, donor anxiety, education (<12 standard), recipient hospital stay (>3 weeks), and, recipient complications (increased creatinine, hemodialysis, lymphocele, and graft dysfunction). The median anxiety scores of donors increased significantly two weeks after operation but later became normal. Caregiver donors have improved QoL scores, despite kidney donation; a larger study is needed.
印度的“照顾者供体”活体亲属肾移植为患者提供了巨大的经济、情感和身体支持。然而，他们的心理健康问题尚未得到关注。我们使用世界卫生组织生活质量（WHOQoL）BREF 评分和医院焦虑抑郁量表（HADS），对 30 对供受者进行了前瞻性研究，分别在术前、移植后两周和三个月进行评估。大多数供者为女性（80%，60%为母亲，28%为妻子），平均年龄为 43.77 ± 10.64 岁（受者为 34.8 ± 9.01 岁）。供者在术后两周和三个月的 WHOQoL BREF 评分均有改善，具体表现为：生理领域（74.30 ± 9.74 分 vs. 78.30 ± 8.20 分；P = 0.001）和（74.30 ± 9.74 分 vs. 86.23 ± 7.25 分；P <0.001）；心理领域（74.90 ± 8.44 分 vs. 82.07 ± 7.19 分；P <0.001）和（74.90 ± 8.44 分 vs. 88.07 ± 6.89 分；P <0.001）；环境领域（75.33 ± 8.09 分 vs. 79.57 ± 6.18 分；P <0.001）和（75.33 ± 8.09 分 vs. 86.97 ± 3.8 分；P <0.001）；社会关系领域（77.73 ± 8.28 分 vs. 79.77 ± 7.99 分；P <0.001）和（77.73 ± 8.28 分 vs. 84.77 ± 7.45 分；P <0.001）。受者的评分相似。具有显著 Pearson 或标准化 beta 系数的因素包括供者年龄 <20 岁、供者并发症、供者焦虑、教育程度（<12 年）、受者住院时间（>3 周）和受者并发症（肌酐升高、血液透析、淋巴囊肿和移植物功能障碍）。供者的焦虑评分在术后两周显著升高，但后来恢复正常。尽管进行了肾移植，但照顾者供体的生活质量评分仍有改善，还需要更大规模的研究。
