Varadharajan Natarajan, Grover Sandeep
Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Ind Psychiatry J. 2021 Jul-Dec;30(2):285-290. doi: 10.4103/ipj.ipj_91_19. Epub 2021 Aug 19.
To evaluate the prevalence of risk for obstructive sleep apnea (OSA) among patients with bipolar disorder (BD).
Eighty-seven patients with BD and 50 matched controls were assessed by using the Berlin questionnaire.
One-fifth of the patients with BD was found to be at high risk for OSA, compared to the 6% prevalence in the control group. Patients in high risk for OSA were more often females, had significantly higher body mass index, high waist circumference, and comorbid physical illnesses. In terms of pharmacotherapy, there was association of use of antipsychotics with higher risk of OSA at the trend level (p=0.052).
The prevalence of high risk for OSA is significantly higher among patients with BD and higher prevalence is related to obesity and comorbid physical illnesses.
评估双相情感障碍（BD）患者中阻塞性睡眠呼吸暂停（OSA）风险的患病率。
采用柏林问卷对87例BD患者和50例匹配的对照组进行评估。
发现五分之一的BD患者有患OSA的高风险，而对照组的患病率为6%。OSA高风险患者中女性更为常见，体重指数、腰围显著更高，且伴有躯体疾病。在药物治疗方面，抗精神病药物的使用与OSA较高风险在趋势水平上存在关联（p=0.052）。
BD患者中OSA高风险的患病率显著更高，且较高的患病率与肥胖和躯体疾病共病有关。
