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评估并比较甲醛甲酚、三氧化矿物凝聚体、电灼术和生物活性玻璃用于人类乳牙牙髓切断术的临床和影像学结果。

To Evaluate and Compare the Clinical and Radiographic Outcomes of Formocresol, Mineral Trioxide Aggregate, Electrocautery, and Bioactive Glass when used for Pulpotomy in Human Primary Teeth.

作者信息

Haideri Safia, Koul Monika, Raj Rachna, Salam Sharib Abdus, Kalim Md Shadab, Gupta Vivek

机构信息

lecturer, Department of Pedodontics and Preventive Dentistry, Patna Dental College and Hospital, Patna, India.

Professor, Department of Pedodontics and Preventive Dentistry, Career Post Graduate Institute of Dental Science, Lucknow, Uttar Pradesh, India.

出版信息

J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S1251-S1258. doi: 10.4103/jpbs.jpbs_23_21. Epub 2021 Nov 10.

Abstract

AIMS

The aim of the present study is to evaluate and compare the clinical and radiographic outcomes of formocresol (FC), mineral trioxide aggregate (MTA), electrocautery, and bioactive glass (BAG) when used for pulpotomy in human primary teeth.

SETTINGS AND DESIGN

The present study comprised of total four Groups A, B, C, and D; the selected children for the procedure were randomly divided into four groups according to the type of agent used as Group A, Group B, Group C, and Group D, respectively, having 20 teeth.

METHODOLOGY

In this study, pulpotomies were performed on the respective teeth. The teeth were treated using either FC, MTA, electrocautery, and BAG. Following the pulpotomy procedure, the teeth were evaluated for the clinical and radiographic success for 3, 6, and 12 months. The teeth were evaluated for the presence of pain, swelling, internal and external resorption, and radiolucency.

STATISTICAL ANALYSIS USED

Fisher's exact test and Yates corrected Chi-square test is used.

RESULTS

After 12 months of follow-up, the clinical and radiographic success rates were high. Comparing the frequency (%) of overall clinical success rate of four groups at 12 months, the Chi-square test revealed significantly different and higher overall clinical success rate in MTA as compared to other groups, especially FC and EC at 12 months. Comparing the frequency (%) of overall radiographic success rate of four groups at 12 months, the Chi-square test revealed significantly different and higher overall radiographic success rate in MTA as compared to other groups, especially FC and EC at 12 months.

CONCLUSIONS

In this study, the success rates of MTA, BAG, and FC are matching their physical and chemical properties which have been detailed and explained earlier.

摘要

目的

本研究旨在评估和比较甲醛甲酚(FC)、三氧化矿物凝聚体(MTA)、电烙术和生物活性玻璃(BAG)用于人类乳牙活髓切断术的临床和影像学结果。

设置与设计

本研究共分为A、B、C、D四组;根据所用药物类型,将入选该手术的儿童随机分为四组,分别为A组、B组、C组和D组,每组20颗牙齿。

方法

在本研究中,对相应牙齿进行活髓切断术。使用FC、MTA、电烙术和BAG对牙齿进行治疗。活髓切断术后,对牙齿进行3个月、6个月和12个月的临床和影像学成功评估。评估牙齿是否存在疼痛、肿胀、内外部吸收以及透射区。

所用统计分析方法

采用Fisher精确检验和Yates校正卡方检验。

结果

随访12个月后,临床和影像学成功率较高。比较四组在12个月时的总体临床成功率频率(%),卡方检验显示,与其他组相比,MTA在12个月时的总体临床成功率显著不同且更高,尤其是与FC和电烙术(EC)相比。比较四组在12个月时的总体影像学成功率频率(%),卡方检验显示,与其他组相比,MTA在12个月时的总体影像学成功率显著不同且更高,尤其是与FC和EC相比。

结论

在本研究中,MTA、BAG和FC的成功率与其先前详细解释的物理和化学性质相符。

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