Lee Jiha, Chang Chiang-Hua, Yung Raymond, Bynum Julie P W
University of Michigan, Ann Arbor.
ACR Open Rheumatol. 2022 Apr;4(4):332-337. doi: 10.1002/acr2.11406. Epub 2022 Jan 17.
We compared disease-modifying antirheumatic drug (DMARD) use for older adults with rheumatoid arthritis (RA)-related ambulatory visits from rheumatologists and primary care providers (PCPs).
In this study of national sample office visits, we characterized ambulatory visits by older adults 65 years of age or older seen by rheumatologists or PCPs for diagnosis of RA using the 2005-2016 National Ambulatory Medical Care Survey. We analyzed patterns and trends of DMARD use using descriptive statistics and multivariable analyses by provider specialty.
We identified 518 observations representing 7,873,246 ambulatory RA visits by older adults over 12 years; 74% were with rheumatologists. Any DMARD use was recorded at 56% of rheumatologist and 30% of PCP visits. Among visits with any DMARD use, 20% of rheumatologist visits had two or more DMARDs compared with 6% of PCP visits. Over the 12-year study period, there was no statistical difference in trend of any or conventional synthetic DMARD use at visits by provider specialty, adjusted for patient characteristics, non-DMARD polypharmacy and multimorbidity. However, biologic DMARD use was more likely to incrementally increase with rheumatologist compared with PCP visits (P = 0.003).
DMARD use for older adults with RA remains low from both rheumatologists and PCPs, including biologic DMARDs, even though American College of Rheumatology guidelines recommend earlier and more aggressive treatment of RA. With predicted shortages in the rheumatology workforce and maldistribution of rheumatology providers, PCPs may play an increasingly important role in caring for older adults with RA. Further research is needed to understand to optimize appropriate use of DMARDs in older patients with RA.
我们比较了老年类风湿关节炎(RA)患者因与RA相关的门诊就诊而使用改善病情抗风湿药(DMARD)的情况,这些就诊分别来自风湿病专科医生和初级保健提供者(PCP)。
在这项针对全国样本门诊就诊的研究中,我们利用2005 - 2016年全国门诊医疗护理调查,对65岁及以上的老年人因诊断RA而接受风湿病专科医生或初级保健提供者诊治的门诊就诊情况进行了描述。我们使用描述性统计和按提供者专业进行的多变量分析来分析DMARD的使用模式和趋势。
我们确定了518条观察记录,代表12年间老年人7873246次门诊RA就诊;其中74%是由风湿病专科医生诊治的。56%的风湿病专科医生门诊和30%的初级保健提供者门诊记录了使用任何DMARD的情况。在使用任何DMARD的就诊中,20%的风湿病专科医生门诊使用了两种或更多种DMARD,而初级保健提供者门诊的这一比例为6%。在12年的研究期间,在对患者特征、非DMARD联合用药和多种疾病进行调整后,按提供者专业划分的门诊中,使用任何或传统合成DMARD的趋势没有统计学差异。然而,与初级保健提供者门诊相比,风湿病专科医生门诊使用生物DMARD的可能性更有可能逐步增加(P = 0.003)。
尽管美国风湿病学会指南建议对RA进行更早、更积极的治疗,但风湿病专科医生和初级保健提供者对老年RA患者使用DMARD的情况仍然较低,包括生物DMARD。鉴于预计风湿病专业人员短缺以及风湿病提供者分布不均,初级保健提供者在照顾老年RA患者方面可能发挥越来越重要的作用。需要进一步研究以了解如何优化老年RA患者DMARD的合理使用。