Department of Radiology, Madi Pain Management Center, Jeonju, Republic of Korea.
Madi Research and Development Center, Jeonju, Republic of Korea.
Pain Physician. 2022 Jan;25(1):E141-E145.
Neuropathic pain in the hands due to carpal tunnel syndrome (CTS) disturbs sleep and affects the quality of life.
We evaluated the effect of ultrasound (US)-guided partial release of the transverse carpal ligament (TCL) using an 18-G needle in patients with refractory CTS.
A prospective outcome study.
The outpatient clinic of a single academic medical center.
This study was prospectively conducted. A total of 155 consecutive patients (191 wrists) with refractory chronic CTS (M:F = 28:127; age = 54.7 ± 9.6 years; pain duration = 50.3 ± 36.3 weeks) were enrolled and underwent US-guided partial release of the TCL using a needle. The pain severity was measured using the Numeric Rating Scale (NRS) at 3 and 6 months after the treatment. Successful treatment outcomes were defined as more than 50% reduction in the NRS score at 6 months after the treatment compared with the score at pre-treatment and NRS score < 3 at 6 months after the treatment without any surgical intervention.
There were 3 dropouts, and 188 wrists were included in the study. No side effects were reported. A total of 162 wrists (86.2%) showed successful treatment outcomes at 6 months after TCL release. Of the 26 wrists which had unsuccessful treatment outcomes, 6 received surgical treatment. The NRS scores at 3- and 6-month post-treatment were significantly reduced: the average NRS scores were 7.1 ± 0.6 at baseline, 1.9 ± 1.7 at 3 months after the treatment, and 1.7 ± 1.7 at 6 months after the treatment.
We conducted our study without a control or a placebo group.
We believe that US-guided partial release of the TCL using a needle can be an effective and safe technique for treating chronic refractory pain due to CTS. It can potentially be attempted before surgical treatment.
腕管综合征(CTS)引起的手部神经病理性疼痛会干扰睡眠并影响生活质量。
我们评估了使用 18G 针行超声(US)引导下腕横韧带(TCL)部分松解术治疗难治性 CTS 的效果。
前瞻性结局研究。
单家学术医学中心的门诊。
本研究为前瞻性研究。共纳入 155 例(191 只腕)难治性慢性 CTS 患者(男女比为 28:127;年龄为 54.7±9.6 岁;疼痛持续时间为 50.3±36.3 周),行 US 引导下 TCL 部分松解术。治疗后 3 个月和 6 个月采用数字评分量表(NRS)评估疼痛严重程度。成功治疗的定义为:与治疗前相比,治疗后 6 个月 NRS 评分降低 50%以上,且治疗后 6 个月 NRS 评分<3 分,无需任何手术干预。
3 例患者失访,共 188 只腕纳入研究。无不良反应报告。162 只(86.2%)腕部治疗后 6 个月取得了成功。26 只(13.8%)腕部治疗效果不佳,其中 6 只接受了手术治疗。治疗后 3 个月和 6 个月时 NRS 评分显著降低:平均基线 NRS 评分为 7.1±0.6,治疗后 3 个月为 1.9±1.7,治疗后 6 个月为 1.7±1.7。
本研究未设立对照组或安慰剂组。
我们认为,使用 18G 针行 US 引导下 TCL 部分松解术是一种治疗 CTS 所致慢性难治性疼痛的有效且安全的技术,可在手术治疗前尝试应用。