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在脐带完整的情况下对早产儿进行稳定治疗期间维持正常体温

Maintaining Normothermia in Preterm Babies during Stabilisation with an Intact Umbilical Cord.

作者信息

Cleator Alexander James, Coombe Emma, Alexopoulou Vasiliki, Levingston Laura, Evans Kathryn, Hurst Jonathan Christopher, Yoxall Charles William

机构信息

Liverpool Women's Hospital, Liverpool L8 7SS, UK.

出版信息

Children (Basel). 2022 Jan 5;9(1):75. doi: 10.3390/children9010075.

DOI:10.3390/children9010075
PMID:35053705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8774544/
Abstract

BACKGROUND

We had experienced an increase in admission hypothermia rates during implementation of deferred cord clamping (DCC) in our unit. Our objective was to reduce the number of babies with a gestation below 32 weeks who are hypothermic on admission, whilst practising DCC and providing delivery room cuddles (DRC).

METHOD

A 12 month quality improvement project set, in a large Neonatal Intensive Care Unit, from January 2020 to December 2020. Monthly rates of admission hypothermia (<36.5 °C) for all eligible babies, were tracked prospectively. Each hypothermic baby was reviewed as part of a series of Plan, Do, Study Act (PDSA) cycles, to understand potential reasons and to develop solutions. Implementation of these solutions included the dissemination of the learning through a variety of methods. The main outcome measure was the proportion of babies who were hypothermic (<36.5 °C) on admission compared to the previous 12 months.

RESULTS

130 babies with a gestation below 32 weeks were admitted during the study period. 90 babies (69.2%) had DCC and 79 babies (60%) received DRC. Compared to the preceding 12 months, the rate of hypothermia decreased from 25/109 (22.3%) to 13/130 (10%) ( = 0.017). Only 1 baby (0.8%) was admitted with a temperature below 36 °C and 12 babies (9.2%) were admitted with a temperature between 36 °C and 36.4 °C. Continued monitoring during the 3 months after the end of the project showed that the improvements were sustained with 0 cases of hypothermia in 33 consecutive admissions.

CONCLUSIONS

It is possible to achieve low rates of admission hypothermia in preterm babies whilst providing DCC and DRC. Using a quality improvement approach with PDSA cycles is an effective method of changing clinical practice to improve outcomes.

摘要

背景

在我们科室实施延迟脐带结扎(DCC)期间,入院时体温过低的发生率有所上升。我们的目标是减少孕周低于32周的婴儿入院时体温过低的数量,同时实施DCC并提供产房肌肤接触(DRC)。

方法

在一家大型新生儿重症监护病房开展了一项为期12个月的质量改进项目,时间为2020年1月至2020年12月。对所有符合条件的婴儿每月入院时体温过低(<36.5°C)的发生率进行前瞻性跟踪。作为一系列计划、执行、研究、改进(PDSA)循环的一部分,对每个体温过低的婴儿进行评估,以了解潜在原因并制定解决方案。这些解决方案的实施包括通过多种方法传播经验教训。主要结局指标是与前12个月相比,入院时体温过低(<36.5°C)的婴儿比例。

结果

研究期间共收治了130例孕周低于32周的婴儿。90例(69.2%)接受了DCC,79例(60%)接受了DRC。与前12个月相比,体温过低的发生率从25/109(22.3%)降至13/130(10%)(P = 0.017)。只有1例婴儿(0.8%)入院时体温低于36°C,12例婴儿(9.2%)入院时体温在36°C至36.4°C之间。项目结束后的3个月内持续监测显示,改进效果得以维持,连续33例入院病例中无体温过低情况。

结论

在提供DCC和DRC的同时,有可能使早产儿入院时体温过低的发生率保持在较低水平。采用PDSA循环的质量改进方法是改变临床实践以改善结局的有效方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/68eb0b72180b/children-09-00075-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/ffd55571591f/children-09-00075-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/98f872a1e634/children-09-00075-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/eafbb78ec599/children-09-00075-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/014efd0e033f/children-09-00075-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/d4a7a6060a74/children-09-00075-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/6a9c12e2f017/children-09-00075-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/c5d37f535a39/children-09-00075-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/ed228ad3d665/children-09-00075-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/68eb0b72180b/children-09-00075-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/ffd55571591f/children-09-00075-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/98f872a1e634/children-09-00075-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/eafbb78ec599/children-09-00075-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/014efd0e033f/children-09-00075-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/d4a7a6060a74/children-09-00075-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/6a9c12e2f017/children-09-00075-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/c5d37f535a39/children-09-00075-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/ed228ad3d665/children-09-00075-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d14/8774544/68eb0b72180b/children-09-00075-g009.jpg

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Resuscitation. 2020 Nov;156:A156-A187. doi: 10.1016/j.resuscitation.2020.09.015. Epub 2020 Oct 21.
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Association between admission temperature and mortality and major morbidity in very low birth weight neonates - single center prospective observational study.极低出生体重儿入院体温与死亡率及主要并发症的关系——单中心前瞻性观察研究。
J Matern Fetal Neonatal Med. 2022 Aug;35(16):3096-3104. doi: 10.1080/14767058.2020.1810229. Epub 2020 Aug 24.
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Effect of delayed cord clamping on stem cell transfusion and hematological parameters in preterm infants with placental insufficiency: a pilot randomized trial.
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Eur J Pediatr. 2021 Jan;180(1):157-166. doi: 10.1007/s00431-020-03730-4. Epub 2020 Jul 4.
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