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经颅与经鼻内镜治疗外伤性脑脊液鼻漏的对比分析。

A Comparative Analysis of Transcranial and Endoscopic Repair for Traumatic CSF Rhinorrhea.

机构信息

Department of Neurosurgery, Medical Trust Hospital, Cochin, Kerala, India.

Department of Neurosurgery, VPS Lakeshore Hospital, Kochi, Kerala, India.

出版信息

J Neurol Surg A Cent Eur Neurosurg. 2023 Sep;84(5):428-432. doi: 10.1055/a-1747-9744. Epub 2022 Jan 21.

DOI:10.1055/a-1747-9744
PMID:35062035
Abstract

BACKGROUND

Surgical treatment of anterior cranial base traumatic cerebrospinal fluid (CSF) rhinorrhea is challenging and is fraught with complications. Whether a person should be offered open craniotomy or endoscopic endonasal repair is a dilemma faced by most surgeons. This study is one of the few to directly compare the two forms of management.

METHODS

Data were collected from two groups of 15 patients each who underwent transcranial CSF leak repair and endoscopic endonasal CSF leak repair in a tertiary care hospital over a 3-year period. Information including demographics, recurrence rates, complications, and hospital and intensive care unit (ICU) stay was recorded and analyzed. Outcome was assessed up to 6 months.

RESULTS

Recurrence was seen in 9/30 patients, 6 in the transcranial group and 3 in the endoscopic group. Hospital stay was longer than 1 week in all the transcranially operated patients and only in 73% of the endoscopically operated patients ( = 0.439) although ICU stay was reduced in the endoscopic group ( = 0.066). Complications were more common with transcranial repair (seven of eight patients who underwent transcranial repair,  = 0.035) with anosmia being the most common (33.3%,  = 0.042).

CONCLUSION

The transcranial open repair is a reasonable choice especially for leaks that occur through the frontal sinus and extend backward into the frontoethmoidal region. However, this approach has the drawbacks of greater number of complications, higher recurrence rate, and longer ICU and overall hospital stay. The endoscopic endonasal repair enjoys a lower morbidity profile although it may not be an adequate treatment for leaks that are placed far laterally in the frontal sinus.

摘要

背景

颅前底创伤性脑脊液(CSF)鼻漏的手术治疗具有挑战性,且并发症风险高。大多数外科医生都面临着一个困境,即应该选择开颅手术还是内镜经鼻修复。本研究是为数不多的直接比较两种治疗方法的研究之一。

方法

在 3 年期间,从一家三级护理医院的两组各 15 名患者中收集数据,他们分别接受了经颅 CSF 漏修复和内镜经鼻 CSF 漏修复。记录并分析了包括人口统计学、复发率、并发症以及住院和重症监护病房(ICU)住院时间等信息。结果评估长达 6 个月。

结果

30 名患者中有 9 名(6 名经颅组和 3 名内镜组)复发。所有经颅手术患者的住院时间均超过 1 周,而仅 73%的内镜手术患者(=0.439)如此(=0.066)。尽管内镜组的 ICU 住院时间减少(=0.066),但经颅修复的并发症更常见(8 名经颅修复患者中有 7 名,=0.035),其中嗅觉丧失最常见(33.3%,=0.042)。

结论

对于从前额窦向后延伸到额筛区的漏口,经颅开放修复是一种合理的选择。然而,这种方法存在更多并发症、更高复发率以及更长的 ICU 和总住院时间的缺点。内镜经鼻修复的发病率较低,尽管它可能不是治疗位于额窦外侧的漏口的充分治疗方法。

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