印度无症状感染者中新冠病毒毒株的全基因组测序
Whole-Genome Sequencing of SARS-CoV-2 Strains from Asymptomatic Individuals in India.
作者信息
Rangaiah Ambica, Shankar Sathyanarayan Muthur, Padukone Shashiraja, Rangappa Kusuma Gowdra, Basawarajappa Shantala Gowdara
机构信息
Department of Microbiology, Bangalore Medical College Research Institute, Bengaluru, Karnataka, India.
出版信息
Microbiol Resour Announc. 2022 Feb 17;11(2):e0085021. doi: 10.1128/MRA.00850-21. Epub 2022 Jan 27.
We performed targeted genome sequencing of 11 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) samples collected from asymptomatic individuals. These nasopharyngeal and oropharyngeal samples were collected during the first wave of coronavirus disease 2019 (COVID-19) in Karnataka, India. Nine strains were found to be Nextstrain clade 20B (PANGO lineage B.1.1.519, GISAID clade GR), and two were identified as clade 20A (PANGO lineage B.1.619, GISAID clade G). The spike protein mutation D614G was observed across all the sequenced strains.
我们对从无症状个体采集的11份严重急性呼吸综合征冠状病毒2（SARS-CoV-2）样本进行了靶向基因组测序。这些鼻咽和口咽样本是在印度卡纳塔克邦2019年冠状病毒病（COVID-19）第一波疫情期间采集的。发现9株属于Nextstrain进化枝20B（PANGO谱系B.1.1.519，GISAID进化枝GR），2株被鉴定为进化枝20A（PANGO谱系B.1.619，GISAID进化枝G）。在所有测序菌株中均观察到刺突蛋白突变D614G。
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