有复杂需求的柬埔寨裔美国人药物治疗问题的风险因素：一项横断面观察性研究。
Risk factors for drug therapy problems among Cambodian Americans with complex needs: a cross-sectional, observational study.
作者信息
Wagner Julie A, Bermudez-Millan Angela, Berthold S Megan, Buckley Thomas, Buxton Orfeu M, Feinn Richard, Kuoch Theanvy, Kong Sengly, Lim Mackenzie, Polomoff Christina, Scully Mary
机构信息
Behavioral Sciences and Community Health, University of Connecticut School of Dental Medicine, Farmington, CT, USA.
Public Health Sciences, University of Connecticut School of Medicine, Farmington, CT, USA.
出版信息
Health Psychol Behav Med. 2022 Jan 24;10(1):145-159. doi: 10.1080/21642850.2021.2021917. eCollection 2022.
BACKGROUND
Pharmaceutical drug therapy problems (DTPs) are a major public health problem. We examined patient-level risk factors for DTPs among Cambodian Americans.
METHODS
Community health workers (CHWs) verbally administered surveys and completed a detailed medication review form with participants. A doctoral-level pharmacist reviewed the form with the patient and CHW to determine DTP number and type (appropriateness, effectiveness, safety, and adherence).
RESULTS
Participants ( = 63) averaged 55 years old, 6 years of education, 52% were married, 87% spoke Khmer at home, with modal household income <$20,000 (41%). The percentage of participants with DTPs was: 45% appropriateness, 25% effectiveness, 64% safety, and 30% adherence, averaging 3.7 DTPs per patient. In multiple regressions, patient characteristics uniquely predicted each type of DTP. In a multiple regression controlling for number of medications, being married reduced total DTPs (IRR = 0.70) and being depressed increased total DTPs (IRR = 1.26).
CONCLUSIONS
Vulnerable patients should be prioritized for pharmacist/CHW teams to identify DTPs. ClinicalTrials.gov identifier: NCT02502929.
背景
药物治疗问题（DTPs）是一个重大的公共卫生问题。我们研究了柬埔寨裔美国人中DTPs的患者层面风险因素。
方法
社区卫生工作者（CHWs）通过口头方式进行调查，并与参与者一起填写详细的用药审查表。一名博士级药剂师与患者和CHW一起审查该表格，以确定DTP的数量和类型（适宜性、有效性、安全性和依从性）。
结果
参与者（n = 63）平均年龄55岁，受教育年限6年，52%已婚，87%在家说高棉语，家庭收入中位数<$20,000（41%）。存在DTPs的参与者百分比分别为：适宜性45%、有效性25%、安全性64%、依从性30%，平均每位患者有3.7个DTPs。在多元回归分析中，患者特征可唯一预测每种类型的DTP。在控制药物数量的多元回归分析中，已婚可降低总的DTPs（风险比=0.70），而抑郁会增加总的DTPs（风险比=
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