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HER2 阳性转移性乳腺癌患者的马尾脊髄内转移:病例报告。

Intramedullary spinal cord metastasis to the cauda equina in a patient with HER2-positive metastatic breast cancer: A case report.

机构信息

Department of Surgery, Keio University School of Medicine, Tokyo, Japan.

Department of Breast Surgery, Saitama Medical Center, Saitama, Japan.

出版信息

Breast Dis. 2022;41(1):155-161. doi: 10.3233/BD-210032.

Abstract

The rate of metastasis to the central nervous system is high in human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer patients. Metastatic cauda equina tumors are characterized by rapid progression of symptoms, thus signifying the requirement of their early treatment. However, these tumors are rarely reported, and their optimal treatment options have not been established yet. Here, we report a case study of a patient with HER2-positive breast cancer that metastasized to the cauda equina. The patient underwent urgent surgery to relieve the spinal cord compression. The pain in her back and lower limbs was greatly reduced. Unfortunately, her ability to walk did not improve sufficiently. Overall, surgical treatment may be a favorable option to improve a patient's quality of life.

摘要

人表皮生长因子受体 2(HER2)阳性转移性乳腺癌患者的中枢神经系统转移率较高。转移性马尾肿瘤的症状进展迅速,因此需要早期治疗。然而,这些肿瘤很少被报道,其最佳治疗方案尚未建立。在这里,我们报告了一例 HER2 阳性乳腺癌转移至马尾的病例。患者接受了紧急手术以缓解脊髓压迫。她的背痛和下肢疼痛大大减轻。不幸的是,她的行走能力没有得到足够的改善。总的来说,手术治疗可能是改善患者生活质量的一个有利选择。

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