Liu Jiayi, Bai Zhijie, Li Shuaiqi, Zeng Sheng, Li Chuang, Liu Qian
The First Central Clinical College of Tianjin Medical University, Tianjin, China.
Department of Urology, Tianjin First Central Hospital, School of Medicine, NanKai University, Tianjin, China.
Front Oncol. 2022 Jan 14;11:810708. doi: 10.3389/fonc.2021.810708. eCollection 2021.
Inflammatory myofibroblastic tumour (IMT), also known as plasma cell granuloma (PCG) or inflammatory pseudotumour (IPT), is a distinctive, rarely metastasizing neoplasm composed of myofibroblastic and fibroblastic spindle cells accompanied by inflammatory infiltration of plasma cells, lymphocytes and/or eosinophils. IMT predominantly affects children and young adults, and the age at presentation ranges from 3 to 89 years. We present a very rare case of recurrent testicular IMT without ALK rearrangement. This case highlights the clinical characteristics and diagnostic factors associated with primary and recurrent foci of this rare tumour, along with key therapeutic approaches.
炎性肌成纤维细胞瘤(IMT),也称为浆细胞性肉芽肿(PCG)或炎性假瘤(IPT),是一种独特的、很少发生转移的肿瘤,由肌成纤维细胞和成纤维细胞梭形细胞组成,并伴有浆细胞、淋巴细胞和/或嗜酸性粒细胞的炎性浸润。IMT主要影响儿童和年轻人,发病年龄范围为3至89岁。我们报告了一例非常罕见的复发性睾丸IMT,无ALK重排。该病例突出了这种罕见肿瘤的原发灶和复发灶相关的临床特征、诊断因素以及关键治疗方法。