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肾脏炎性肌纤维母细胞瘤:一种罕见的肾脏肿瘤。

Inflammatory Myofibroblastic Tumor of the Kidney: A Rare Renal Tumor.

作者信息

Pothadiyil Alvin Jose, Bhat Suresh, Paul Fredrick, Mampatta Jithesh, Srinivas Mahesh

机构信息

Senior Resident, Department of Urology, Goverment Medical College , Kottayam, Kerala, India .

Professor, Department of Urology, Goverment Medical College , Kottayam, Kerala, India .

出版信息

J Clin Diagn Res. 2016 Nov;10(11):ED17-ED18. doi: 10.7860/JCDR/2016/22465.8856. Epub 2016 Nov 1.

Abstract

Inflammatory Myofibroblastic Tumour (IMT) or 'pseudotumour' of the kidney is a rare benign tumour of unknown aetiology affecting mostly young adults. A subset of IMT is neoplastic and harbours translocations of activin receptor-like kinase-1 (ALK-1) gene and can recur or rarely metastasize. Presentation varies from an incidentaloma to gross haematuria. Clinical examination and radiological investigations are usually inconclusive. Often, biopsy is inconclusive necessitating a management similar to that of Renal Cell Cancer (RCC). Diagnosis is based on immunohistochemistry. We are reporting a case of IMT in a 50-year-old male patient who presented with left flank mass which on evaluation was suggestive of left renal cell carcinoma. Excision of the tumour, histopathological examination and Immunohistochemistry proved the tumour to be IMT.

摘要

炎性肌纤维母细胞瘤(IMT)或肾脏“假瘤”是一种病因不明的罕见良性肿瘤,主要影响年轻人。IMT的一个亚群具有肿瘤性,携带激活素受体样激酶-1(ALK-1)基因易位,可复发或很少转移。表现从偶发瘤到肉眼血尿不等。临床检查和影像学检查通常无定论。活检往往也无定论,因此治疗方式与肾细胞癌(RCC)相似。诊断基于免疫组织化学。我们报告一例50岁男性IMT患者,该患者以左侧腰部肿块就诊,评估提示左肾细胞癌。肿瘤切除、组织病理学检查和免疫组织化学证实该肿瘤为IMT。

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Inflammatory pseudotumor of the kidney.肾脏炎性假瘤
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Inflammatory myofibroblastic tumours: where are we now?炎性肌纤维母细胞瘤:我们目前的进展如何?
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