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2017/2023年0至5岁儿童呼吸道感染的住院情况

Hospital Admissions for Respiratory Tract Infections in Children Aged 0-5 Years for 2017/2023.

作者信息

Methi Fredrik, Størdal Ketil, Telle Kjetil, Larsen Vilde Bergstad, Magnusson Karin

机构信息

Cluster for Health Services Research, Norwegian Institute of Public Health, Oslo, Norway.

Department of Pediatric Research, University of Oslo, Oslo, Norway.

出版信息

Front Pediatr. 2022 Jan 12;9:822985. doi: 10.3389/fped.2021.822985. eCollection 2021.

Abstract

To compare hospital admissions across common respiratory tract infections (RTI) in 2017-21, and project possible hospital admissions for the RTIs among children aged 0-12 months and 1-5 years in 2022 and 2023. In 644 885 children aged 0-12 months and 1-5 years, we plotted the observed monthly number of RTI admissions [upper- and lower RTI, influenza, respiratory syncytial virus (RSV), and COVID-19] from January 1st, 2017 until October 31st, 2021. We also plotted the number of RTI admissions with a need for respiratory support. We used the observed data to project four different scenarios of RTI admissions for the rest of 2021 until 2023, with different impacts on hospital wards: (1) "Business as usual," (2) "Continuous lockdown," (3) "Children's immunity debt," and (4) "Maternal and child immunity debt." By October 31st, 2021, the number of simultaneous RTI admissions had exceeded the numbers usually observed at the typical season peak in January, i.e., ~900. Based on our observed data and assuming that children and their mothers (who transfer antibodies to the very youngest) have not been exposed to RTI over the last one and a half years, our scenarios suggest that hospitals should be prepared to handle two as many RTI admissions, and two as many RTI admissions requiring respiratory support among 0-5-year-olds as normal, from November 2021 to April 2022. Scenarios with immunity debt suggest that pediatric hospital wards and policy makers should plan for extended capacity.

摘要

比较2017年至2021年常见呼吸道感染(RTI)的住院情况,并预测2022年和2023年0至12个月及1至5岁儿童RTI可能的住院人数。在644885名0至12个月及1至5岁的儿童中,我们绘制了2017年1月1日至2021年10月31日期间观察到的每月RTI住院人数[上呼吸道和下呼吸道RTI、流感、呼吸道合胞病毒(RSV)和新冠病毒病(COVID-19)]。我们还绘制了需要呼吸支持的RTI住院人数。我们利用观察到的数据预测了2021年剩余时间至2023年RTI住院的四种不同情况,对医院病房有不同影响:(1)“照常营业”,(2)“持续封锁”,(3)“儿童免疫债”,以及(4)“母婴免疫债”。到2021年10月31日,同时发生的RTI住院人数已超过通常在1月典型季节高峰时观察到的人数,即约900人。根据我们观察到的数据,并假设儿童及其母亲(将抗体传递给最小儿童的人)在过去一年半中未接触过RTI,我们的预测情况表明,从2021年11月到2022年4月,医院应做好准备,应对0至5岁儿童中RTI住院人数是正常情况两倍的情况,以及需要呼吸支持的RTI住院人数是正常情况两倍的情况。免疫债的预测情况表明,儿科医院病房和政策制定者应规划扩大容量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e91/8790534/eb1f0f51d0f0/fped-09-822985-g0001.jpg

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