Himi T, Kagaya A, Yoshida K, Morooka N, Watanabe S, Masuda Y, Inagaki Y, Endo M, Yamazaki T, Tateno Y
Third Department of Internal Medicine, Chiba University School of Medicine.
J Cardiol. 1987 Dec;17(4):831-6.
Positron emission computed tomography (PET) is regarded an excellent technique for quantitative measurements. However, its accuracy is related to the spatial resolution of the system. The relation between myocardial wall thicknesses as measured by X-ray CT or MRI and the radioactivity as measured using PET was studied in 37 patients. 1. In patients with transmural infarction, the infarcted myocardium was imaged as a region of low radioactivity. However, the myocardium usually exhibited wall thinning, so that partial volume effects must be taken into account in evaluating the radioactivity. 2. In the infarcted regions, the regions of the low radioactivity tended to be larger than those of wall thinning. 3. There were cases with the regional low radioactivity without wall thinning in myocardial infarction and in hypertrophic cardiomyopathy. Because patients with myocardial infarction frequently had regional wall thinning, it seems necessary to correct partial volume effects for the infarcted regions which differ from the normal. It was concluded that, to estimate regional myocardial blood flow or metabolism using PET, it is necessary to supplement another morphological diagnostic method to evaluate myocardial wall thickness.
正电子发射计算机断层扫描（PET）被认为是一种用于定量测量的优秀技术。然而，其准确性与系统的空间分辨率有关。对37例患者进行了研究，以探讨通过X射线计算机断层扫描（CT）或磁共振成像（MRI）测量的心肌壁厚度与使用PET测量的放射性之间的关系。1. 在透壁性梗死患者中，梗死心肌成像为低放射性区域。然而，心肌通常表现出壁变薄，因此在评估放射性时必须考虑部分容积效应。2. 在梗死区域，低放射性区域往往比壁变薄区域更大。3. 在心肌梗死和肥厚型心肌病中，存在无壁变薄的局部低放射性病例。由于心肌梗死患者经常出现局部壁变薄，似乎有必要对与正常情况不同的梗死区域校正部分容积效应。得出的结论是，为了使用PET估计局部心肌血流或代谢，有必要补充另一种形态学诊断方法来评估心肌壁厚度。
