Kovács Krisztina, Tóth Tünde, Wojnárovits László
Institute for Energy Security and Environmental Safety, Centre for Energy Research, Konkoly-Thege Miklós út 29-33, H-1121, Budapest, Hungary E-mail:
Water Sci Technol. 2022 Jan;85(2):685-705. doi: 10.2166/wst.2021.631.
This study summarizes the results of scientific investigations on the removal of the three most often used β-blockers (atenolol, metoprolol and propranolol) by various advanced oxidation processes (AOP). The free radical chemistry, rate constants, degradation mechanism and elimination effectiveness of these compounds are discussed together with the technical details of experiments. In most AOP the degradation is predominantly initiated by hydroxyl radicals. In sulfate radical anion-based oxidation processes (SROP) both hydroxyl radicals and sulfate radical anions greatly contribute to the degradation. The rate constants of reactions with these two radicals are in the 10-10 M s range. The degradation products reflect ipso attack, hydroxylation on the aromatic ring and/or the amino moiety and cleavage of the side chain. Among AOP, photocatalysis and SROP are the most effective for degradation of the three β-blockers. The operating parameters have to be optimized to the most suitable effectiveness.
本研究总结了通过各种高级氧化工艺（AOP）去除三种最常用β受体阻滞剂（阿替洛尔、美托洛尔和普萘洛尔）的科学研究结果。讨论了这些化合物的自由基化学、速率常数、降解机理和去除效果以及实验的技术细节。在大多数AOP中，降解主要由羟基自由基引发。在基于硫酸根阴离子的氧化工艺（SROP）中，羟基自由基和硫酸根阴离子都对降解有很大贡献。与这两种自由基反应的速率常数在10⁻¹⁰ M⁻¹ s⁻¹范围内。降解产物反映了原位进攻、芳环和/或氨基部分的羟基化以及侧链的断裂。在AOP中，光催化和SROP对三种β受体阻滞剂的降解最有效。操作参数必须优化以达到最合适的效果。
