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Concurrent Small-Cell Transformation and Emergence of -C797S and T790M Mutations Under Sequential Treatment With EGFR Inhibitors in Lung Adenocarcinoma.

作者信息

Pizzutilo Elio G, Lauricella Calogero, Cerea Giulio, Giannetta Laura G, Tomasello Gianluca, Stabile Stefano, Motta Valentina, Alexiadis Spyridon, Scaglione Francesco, Vanzulli Angelo, Torre Massimo, Bonoldi Emanuela, Veronese Silvio M, Siena Salvatore, Sartore-Bianchi Andrea

机构信息

Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.

Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan, Italy.

出版信息

JCO Precis Oncol. 2019 Dec;3:1-5. doi: 10.1200/PO.19.00229.

DOI:10.1200/PO.19.00229
PMID:35100737
Abstract
摘要

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Advanced lung adenocarcinoma harboring uncommon EGFR 19 Del and T790M/trans-C797S mutations after resistance: a case report and literature review.耐药后携带罕见EGFR 19缺失和T790M/反式C797S突变的晚期肺腺癌：一例报告及文献复习
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