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《脑着火了:基于影像学的自身免疫性脑炎综述》

Brain on fire: an imaging-based review of autoimmune encephalitis.

机构信息

Department of Radiology, University of Texas Southwestern, 5323 Harry Hines Blvd., Dallas, TX 75390, United States of America.

Department of Radiology, University of Texas Southwestern, 5323 Harry Hines Blvd., Dallas, TX 75390, United States of America.

出版信息

Clin Imaging. 2022 Apr;84:1-30. doi: 10.1016/j.clinimag.2021.12.011. Epub 2021 Dec 31.

Abstract

Autoimmune encephalitis represents an increasingly recognized group of immune-mediated disorders the affect the central nervous system. The purpose of this article is to highlight the characteristic MR imaging findings associated with autoimmune encephalitis, describe the pathophysiology, review antibodies that have been identified and their patterns of CNS involvement, and discuss approaches to management. Familiarity with the imaging and clinical features of autoimmune encephalitis will prompt the radiologist to suggest the diagnosis which can facilitate appropriate management.

摘要

自身免疫性脑炎是一组日益被认识的中枢神经系统免疫介导性疾病。本文旨在强调自身免疫性脑炎的特征性磁共振成像表现,描述其病理生理学,复习已确定的抗体及其对中枢神经系统的累及模式,并讨论治疗方法。熟悉自身免疫性脑炎的影像学和临床表现可促使放射科医生提示诊断,从而有助于进行适当的治疗。

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