胶质瘤患者术前心理人格特质与其主要照顾者心理困扰之间的相关性。

Correlation between preoperative psychological personality traits of glioma patients and psychological distress in their primary caregivers.

作者信息

Zhang Liying, Jiang Lin, Chen Chaoyi, Wang Ke, Xiang Wei, Li Shenjie, Ming Yang, Chen Ligang, Yang Changmei, Zhou Jie

机构信息

Nursing of school, Southwest Medical University, Taiping Street 25#, Lu Zhou 646000, China; Affiliated Hospital of Southwest Medical University, Taiping Street 25#, Lu Zhou 646000, China.

Affiliated Hospital of Southwest Medical University, Taiping Street 25#, Lu Zhou 646000, China; Sichuan Clinical Research Center for Neurosurgery, Taiping Street 25#, Lu Zhou 646000, China; Academician (Expert) Workstation of Sichuan Province, Taiping Street 25#, Lu Zhou 646000, China; Laboratory of Neurosurgery Diseases and Brain Function, Taiping Street 25#, Lu Zhou, 646000, China.

出版信息

Clin Neurol Neurosurg. 2022 Mar;214:107144. doi: 10.1016/j.clineuro.2022.107144. Epub 2022 Jan 25.

DOI:10.1016/j.clineuro.2022.107144

PMID:35101779

Abstract

OBJECTIVE

To explore the relationship between preoperative psychological personality traits of glioma patients and preoperative psychological distress of their primary caregivers.

METHODS

A retrospective analysis was conducted on 85 glioma patients (tumor group) who were admitted to our hospital from February 2016 to December 2018 and 85 primary caregivers. Forty-one healthy volunteers were used as controls.

RESULTS

The scores of 9 scales of the Minnesota Multiphasic Personality Inventory (MMPI) increased significantly in the tumor group compared to the healthy controls (P < 0.05), including L (lie): [(56.0 ± 11.5 vs. 50.0 ± 10.0)], F (fake): [(53.0 ± 10.6 vs. 41.7 ± 8.8)], Hs (hypochondriasis): [(55.6 ± 11.2 vs. 44.2 ± 8.3)], D (depressive personality): [(49.2 ± 9.6 vs. 42.2 ± 10.3)], Mf (masculinity-femininity): [(49.9 ± 9.4 vs. 42.8 ± 14.0)], Pt (psychasthenia): [(51.5 ± 10.0 vs. 40.9 ± 11.5)], Sc (schizophrenia): [(51.2 ± 10.6 vs. 40.2 ± 10.6)], Ma (hypomania): [(51.8 ± 9.1 vs. 47.7 ± 9.4)] and Si (social introversion): [(46.6 ± 8.7 vs. 36.7 ± 13.0)]. However, the K (defensive responses) scale score in the tumor group decreased significantly (52.1 ± 13.9 vs. 58.8 ± 12.1, P = 0.009). The F (fake): [(r=0.253, P=0.019 / r=0.215, P=0.048)], Hs (hypochondriasis): [(r=0.310, P=0.004 / r=0.345, P=0.001)], Pt (psychasthenia): [(r=0.299, P=0.006 / r=0.258, P=0.017)], and Sc (schizophrenia): [(r=0.325,P=0.002/r=0.322, P=0.003)] of preoperative glioma patients were positively correlated with their preoperative psychological distress (depression/anxiety); the D (depressive personality): [(r=0.229, P=0.035)] of preoperative glioma patients was positively correlated with the preoperative depression symptoms of their primary caregivers, and the Hy (hysteria): [(r=0.233, P=0.002)] and Pd (psychopathic deviate): [(r=0.215, P=0.006)] of preoperative glioma patients were positively correlated with the preoperative anxiety symptoms of their primary caregivers.

CONCLUSIONS

The preoperative psychological personality traits of glioma patients were positively correlated with preoperative symptoms of depression and anxiety in primary caregivers.

摘要

目的

探讨胶质瘤患者术前心理人格特质与其主要照顾者术前心理困扰之间的关系。

方法

对2016年2月至2018年12月我院收治的85例胶质瘤患者（肿瘤组）及其85名主要照顾者进行回顾性分析。选取41名健康志愿者作为对照组。

结果

与健康对照组相比，肿瘤组明尼苏达多相人格调查表（MMPI）9个分量表得分显著升高（P<0.05），包括L（说谎）：[（56.0±11.5对50.0±10.0）]、F（伪装）：[（53.0±10.6对41.7±8.8）]、Hs（疑病）：[（55.6±11.2对44.2±8.3）]、D（抑郁性人格）：[（49.2±9.6对42.2±10.3）]、Mf（男性化-女性化）：[（49.9±9.4对42.8±14.0）]、Pt（精神衰弱）：[（51.5±10.0对40.9±11.5）]、Sc（精神分裂症）：[（51.2±10.6对40.2±10.6）]、Ma（轻躁狂）：[（51.8±9.1对47.7±9.4）]和Si（社会内向）：[（46.6±8.7对36.7±13.0）]。然而，肿瘤组K（防御反应）分量表得分显著降低（52.1±13.9对58.8±12.1，P=0.009）。术前胶质瘤患者的F（伪装）：[（r=0.253，P=0.019/r=0.215，P=0.048）]、Hs（疑病）：[（r=0.310，P=0.004/r=0.345，P=0.001）]、Pt（精神衰弱）：[（r=0.299，P=0.006/r=0.258，P=0.017）]和Sc（精神分裂症）：[（r=0.325，P=0.002/r=0.322，P=0.003）]与其术前心理困扰（抑郁/焦虑）呈正相关；术前胶质瘤患者的D（抑郁性人格）：[（r=0.229，P=0.035）]与其主要照顾者术前抑郁症状呈正相关，术前胶质瘤患者的Hy（癔症）：[（r=0.233，P=0.002）]和Pd（精神病态偏差）：[（r=0.215，P=0.006）]与其主要照顾者术前焦虑症状呈正相关。