Department of Medicine, Lagos State University College of Medicine, Ikeja, Nigeria.
Department of Surgery, Lagos State University College of Medicine, Ikeja, Nigeria.
Niger Postgrad Med J. 2022 Jan-Mar;29(1):70-73. doi: 10.4103/npmj.npmj_631_21.
Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent genetic disorder that results in end-stage renal disease. Although ADPKD patients experience long disease trajectories, factors such as hypertension, proteinuria and renal calculi have been observed to lead to rapid renal function impairment in patients with ADPKD. Furthermore, due to the distorted anatomy that makes access to stone difficult, the management of nephrolithiasis in ADPKD patients is one of the several special situations in which urinary lithiasis presents management challenges. We report the case of a 30-year-old male with ADPKD and renal function impairment as a result of multiple obstructive calculi who was treated in Dialyser Medical Centre, Oshodi, Lagos, with Frequency-Doubled Double-Pulse Neodymium: Yttrium - Aluminium Garnet laser (FREDDY laser) lithotripsy, highlighting the possible advantage of FREDDY laser over other types of laser procedures given the minimal tissue-damaging potential of the laser type.
常染色体显性多囊肾病（ADPKD）是最常见的遗传疾病，可导致终末期肾病。尽管 ADPKD 患者经历了较长的疾病进程，但高血压、蛋白尿和肾结石等因素已被观察到可导致 ADPKD 患者的肾功能迅速受损。此外，由于解剖结构扭曲使得结石难以取出，因此 ADPKD 患者的肾结石管理是尿石症呈现管理挑战的几种特殊情况之一。我们报告了一例 30 岁男性病例，该患者患有 ADPKD，由于多发性梗阻性结石导致肾功能受损，在拉各斯奥绍迪的 Dialyser Medical Centre 接受了倍频双脉冲钕：钇-铝石榴石激光（FREDDY 激光）碎石术治疗，强调了在激光类型对组织损伤最小的情况下，FREDDY 激光相对于其他类型的激光手术可能具有优势。
