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1例遗传性血色素沉着症患者感染嗜水气单胞菌的罕见病例。

A Rare Case of Aeromonas Hydrophila Infection in a Patient With Hereditary Hemochromatosis.

作者信息

Obeidat Adham E, Wong Linda L, Fujii-Lau Larissa

机构信息

Internal Medicine, University of Hawaii, Honolulu, USA.

Surgery, University of Hawaii, Honolulu, USA.

出版信息

Cureus. 2021 Dec 22;13(12):e20612. doi: 10.7759/cureus.20612. eCollection 2021 Dec.

Abstract

Hereditary hemochromatosis (HH) is a genetic disorder characterized by abnormal iron metabolism, which leads to elevated serum iron levels and iron tissue deposition. This can suppress immunity and increase pathogen virulence, increasing the susceptibility to serious infections. We present a case of a 76-year-old man with a history of HH, who was later found to have pancreatic adenocarcinoma. He underwent a pancreaticoduodenectomy that was complicated by an unusual septicemia that leads to death. It is important for physicians to appreciate the potential for highly unusual and life-threatening infections in the management of patients with HH.

摘要

遗传性血色素沉着症(HH)是一种以铁代谢异常为特征的遗传性疾病,可导致血清铁水平升高和铁在组织中沉积。这会抑制免疫力并增加病原体的毒力,从而增加严重感染的易感性。我们报告一例76岁有HH病史的男性患者,该患者后来被发现患有胰腺腺癌。他接受了胰十二指肠切除术,但术后并发了一种罕见的败血症,最终导致死亡。对于医生来说,在管理HH患者时认识到发生极其罕见且危及生命的感染的可能性非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45db/8782628/cb2b33c79944/cureus-0013-00000020612-i01.jpg

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