酿酒酵母中化学诱导非整倍体的检测：有丝分裂和减数分裂系统的评估
The detection of chemically induced aneuploidy in Saccharomyces cerevisiae: an assessment of mitotic and meiotic systems.
作者信息
Resnick M A, Mayer V W, Zimmermann F K
出版信息
Mutat Res. 1986 Jan-Mar;167(1-2):47-60. doi: 10.1016/0165-1110(86)90008-4.
PMID:3510376
Abstract
Several systems have been evaluated for their ability to detect aneuploidy. Chromosome gain can be detected in mitotic haploid cells as well as meiotically derived haploid spores. Both chromosome gain and loss are detectable in mitotic diploid cells. Several chemicals have been identified that clearly induce aneuploidy in at least one or more of the systems.
摘要
已有多个系统对其检测非整倍体的能力进行了评估。在有丝分裂单倍体细胞以及减数分裂产生的单倍体孢子中均可检测到染色体增加。在有丝分裂二倍体细胞中，染色体增加和丢失都能被检测到。已鉴定出几种化学物质，它们在至少一个或多个系统中能明确诱导非整倍体的产生。
Zotero 插件