Cerkez V, Tos M, Mygind N
Arch Otolaryngol Head Neck Surg. 1986 Mar;112(3):316-20. doi: 10.1001/archotol.1986.03780030080016.
Goblet-cell density and distribution were studied in ten specimens of the human adult lung. The bronchial tree of the left upper lobe was dissected, and the bronchial mucosa separated and stained by the whole-mount periodic acid-Schiffalcian blue method. There was a significant fall in the goblet-cell density from the proximal to the distal airways. In the upper division, the number decreased from 144 cells per field (second generation) to 80 cells per field (14th generation), and in the lingular division it decreased from 137 (fourth generation) to 77 cell (18th generation). The overall goblet-cell density for the upper lobe was 113 cells per field, corresponding to 6,400 cells per square millimeter. No particular pattern in cell distribution was noticed; the cells were irregularly distributed all along the bronchial tree without any well-defined distribution pattern. In the ten lung specimens studied, goblet-cell density did not correlate with smoking habit, sex, or age.
对10例成人肺标本的杯状细胞密度和分布进行了研究。解剖左肺上叶的支气管树,分离支气管黏膜,采用整装高碘酸-希夫阿尔辛蓝法进行染色。从近端气道到远端气道,杯状细胞密度显著下降。在上叶,细胞数量从每视野144个细胞(第二代)降至每视野80个细胞(第14代);在舌叶,细胞数量从137个(第四代)降至77个(第18代)。上叶的杯状细胞总体密度为每视野113个细胞,相当于每平方毫米6400个细胞。未观察到细胞分布的特定模式;细胞沿支气管树不规则分布,没有明确的分布模式。在所研究的10例肺标本中,杯状细胞密度与吸烟习惯、性别或年龄无关。