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风湿性心脏瓣膜手术后心房颤动:发生率、预测因素和结局。

Atrial Fibrillation after Rheumatic Heart Valve Surgery: Incidence, Predictors, and Outcomes.

机构信息

General Surgery Department, Jordan University of Science and Technology, Irbid, Jordan.

Department of Public Health, Jordan University of Science and Technology, Irbid, Jordan.

出版信息

Thorac Cardiovasc Surg. 2023 Jun;71(4):297-306. doi: 10.1055/s-0041-1740985. Epub 2022 Feb 2.

DOI:10.1055/s-0041-1740985
PMID:35108734
Abstract

BACKGROUND

Atrial fibrillation after cardiac surgery (AFACS) impacts 10 to 65% of patients. AFACS is associated with stroke and other systemic embolic manifestations.

METHODS

Patients at our hospital who underwent valve surgery procedures including aortic valve replacement (AVR), mitral valve replacement (MVR), AVR with coronary artery bypass grafting (CABG), MVR with CABG, or AVR and MVR with/without CABG were included in this study in the period from .

RESULTS

In total, 346 patients were included in the current analysis, with a mean age of 51.6 ± 16.1 years, and 51% were males. .: Univariate predictors of AFACS included age, gender, body mass index (BMI), operation type, ejection fraction (EF), left atrial (LA) diameter, previous history of AF, use of aldosterone antagonists a month before surgery, use of diuretics a month before surgery, length of ICU stay, total length of stay, cross-clamp time 90 minutes, pump time 120 minutes, postoperative acute kidney injury, left ventricular dimensions.By multivariate analysis, only age ( = 0.028, AOR = 10.6), male gender ( = 0.021, ), type of surgery ( = 0.034, AOR = 7.12), history of AF ( = 0.018, AOR = : ), BMI ( < 0.001, ), EF before surgery ( ≤ 0.001, AOR = ), and LA diameter ( = 0.0051, AOR = 18.23) were independent predictors of AFACS.

CONCLUSION

This study identifies risk factors associated with the development of atrial fibrillation after rheumatic valve heart surgery. Older patients, male gender, type of surgery, preoperative AF, BMI, EF before surgery, and LA diameter are independent predictors of AF after cardiac valve surgery.

摘要

背景

心脏手术后心房颤动(AFACS)影响 10%至 65%的患者。AFACS 与中风和其他全身性栓塞表现有关。

方法

本研究纳入了在 期间在我院接受瓣膜手术的患者,包括主动脉瓣置换术(AVR)、二尖瓣置换术(MVR)、AVR 加冠状动脉旁路移植术(CABG)、MVR 加 CABG 或 AVR 和 MVR 加/不加 CABG。

结果

共有 346 例患者纳入本分析,平均年龄为 51.6±16.1 岁,51%为男性。单因素预测因素包括年龄、性别、体重指数(BMI)、手术类型、射血分数(EF)、左心房(LA)直径、既往 AF 史、术前 1 个月使用醛固酮拮抗剂、术前 1 个月使用利尿剂、ICU 住院时间、总住院时间、体外循环时间 90 分钟、泵时间 120 分钟、术后急性肾损伤、左心室大小。多因素分析显示,只有年龄( = 0.028,OR = 10.6)、男性( = 0.021,)、手术类型( = 0.034,OR = 7.12)、AF 史( = 0.018,OR = :)、BMI( < 0.001,)、术前 EF(≤ 0.001,OR = )和 LA 直径( = 0.0051,OR = 18.23)是 AFACS 的独立预测因素。

结论

本研究确定了与风湿性心脏瓣膜手术后心房颤动发展相关的危险因素。年龄较大的患者、男性、手术类型、术前 AF、BMI、术前 EF 和 LA 直径是心脏瓣膜手术后发生 AF 的独立预测因素。

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引用本文的文献

1
Enlargement of the Left Atrium Strongly Predicts Postoperative Mortality Following Heart Valve Surgery.左心房扩大强烈预测心脏瓣膜手术后的术后死亡率。
Vasc Health Risk Manag. 2022 Sep 30;18:783-791. doi: 10.2147/VHRM.S380463. eCollection 2022.