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小细胞肺癌的外科治疗:单中心经验与生存情况

Surgical Treatment in Small-Cell Lung Cancer: Single-Center Experience and Survival.

作者信息

Ulusan Ahmet, Tunca İbrahim Emre, Şanlı Maruf, Işık Ahmet Feridun

机构信息

Department of Thoracic Surgery, Gaziantep University Faculty of Medicine, Gaziantep, Turkey.

出版信息

Turk Thorac J. 2021 May;22(3):237-241. doi: 10.5152/TurkThoracJ.2021.19140.

Abstract

OBJECTIVE

To evaluate the clinical outcomes of patients with different stages of small-cell lung cancer (SCLC) who underwent surgical treatment.

MATERIAL AND METHODS

This retrospective study consisted of 13 patients with SCLC at a tertiary care health center. This study was conducted between 2011 and 2018 at Gaziantep University Faculty of Medicine, Thoracic Surgery Department. Patient follow-up data were collected from medical files. Patients were analyzed according to age, sex, site of resection, clinical stage, pathological stage, recurrence, operation type, chemotherapy, radiotherapy.

RESULTS

The study group consisted of 3 females and 10 males (n = 13). The mean age of the patients was 65 ± 9.3 (52-85) years. The most common location of the primary tumor was the right upper lobe (6 patients, 46.2%). The mean tumor size was 4.36 ± 2.38 cm (1-8.5). In our study, 3 patients had already metastases (2 brain and 1 had metastases in more than 2 anatomic sites). Patients with solitary metastases, who underwent lung resection and metastasis excision had similar survival according to patients without metastases.

CONCLUSION

Our results show that surgical treatment in SCLC could be contributed to the survival of patients. Therefore, patients must be given a chance for surgery, especially considering that the advances in diagnostic and surgical capabilities have increased the likelihood of early diagnosis and effective surgery.

摘要

目的

评估接受手术治疗的不同分期小细胞肺癌(SCLC)患者的临床结局。

材料与方法

这项回顾性研究纳入了一家三级医疗保健中心的13例SCLC患者。本研究于2011年至2018年在加济安泰普大学医学院胸外科进行。患者随访数据从医疗档案中收集。根据年龄、性别、切除部位、临床分期、病理分期、复发情况、手术类型、化疗、放疗对患者进行分析。

结果

研究组包括3名女性和10名男性(n = 13)。患者的平均年龄为65±9.3(52 - 85)岁。原发肿瘤最常见的部位是右上叶(6例,46.2%)。平均肿瘤大小为4.36±2.38 cm(1 - 8.5)。在我们的研究中,3例患者已有转移(2例脑转移,1例在2个以上解剖部位有转移)。接受肺切除和转移灶切除的孤立转移患者与无转移患者的生存率相似。

结论

我们的结果表明,SCLC的手术治疗有助于患者生存。因此,必须给予患者手术机会,特别是考虑到诊断和手术能力的进步增加了早期诊断和有效手术的可能性。

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