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原发性硬化性胆管炎和自身免疫性肝炎重叠综合征并发溃疡性结肠炎。

Primary Sclerosing Cholangitis and Autoimmune Hepatitis Overlapping Syndrome Complicated by Ulcerative Colitis.

机构信息

Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Japan.

出版信息

Intern Med. 2022 Aug 15;61(16):2471-2475. doi: 10.2169/internalmedicine.8866-21. Epub 2022 Feb 1.

DOI:10.2169/internalmedicine.8866-21
PMID:35110488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9449607/
Abstract

The case of a 28-year-old man who had primary sclerosing cholangitis and autoimmune hepatitis overlapping syndrome (PSC-AIH OS) complicated by ulcerative colitis (UC) is reported. First, he was diagnosed with PSC complicated by UC and initially treated with ursodeoxycholic acid and mesalazine. Twenty-four months later, liver damage reappeared, and we performed a liver biopsy, which showed the features of AIH. We eventually diagnosed him with PSC-AIH OS complicated by UC. If liver damage worsens in PSC patients, PSC-AIH OS should be considered. The optimum management approach for PSC-AIH OS should be established.

摘要

报告了一例 28 岁男性原发性硬化性胆管炎和自身免疫性肝炎重叠综合征（PSC-AIH OS）合并溃疡性结肠炎（UC）的病例。首先，他被诊断为 PSC 合并 UC，并最初接受熊去氧胆酸和美沙拉嗪治疗。24 个月后，肝损伤再次出现，我们进行了肝活检，显示出 AIH 的特征。我们最终诊断为 PSC-AIH OS 合并 UC。如果 PSC 患者的肝损伤恶化，应考虑 PSC-AIH OS。应建立 PSC-AIH OS 的最佳管理方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e2b/9449607/3c4d9cec98b8/1349-7235-61-2471-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e2b/9449607/defc288472f9/1349-7235-61-2471-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e2b/9449607/0e49ab48a8ea/1349-7235-61-2471-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e2b/9449607/3c4d9cec98b8/1349-7235-61-2471-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e2b/9449607/defc288472f9/1349-7235-61-2471-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e2b/9449607/0e49ab48a8ea/1349-7235-61-2471-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e2b/9449607/3c4d9cec98b8/1349-7235-61-2471-g003.jpg

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本文引用的文献

1
Long-term outcomes of pediatric-onset primary sclerosing cholangitis: A single-center experience in Japan.儿童期起病的原发性硬化性胆管炎的长期预后：日本单中心经验
Hepatol Res. 2019 Dec;49(12):1386-1397. doi: 10.1111/hepr.13421. Epub 2019 Sep 11.
2
Two Cases of Primary Sclerosing Cholangitis Overlapping with Autoimmune Hepatitis in Adults.两例成人原发性硬化性胆管炎合并自身免疫性肝炎病例
Intern Med. 2017;56(5):509-515. doi: 10.2169/internalmedicine.56.7633. Epub 2017 Mar 1.
3
The 2016 diagnostic criteria for primary sclerosing cholangitis.
溃疡性结肠炎并发原发性硬化性胆管炎和自身免疫性肝炎重叠综合征：病例报告及文献复习。
Front Immunol. 2023 May 9;14:1132072. doi: 10.3389/fimmu.2023.1132072. eCollection 2023.
原发性硬化性胆管炎 2016 年诊断标准。
J Gastroenterol. 2017 Jul;52(7):838-844. doi: 10.1007/s00535-016-1286-x. Epub 2016 Dec 5.
4
Primary Sclerosing Cholangitis.原发性硬化性胆管炎
N Engl J Med. 2016 Sep 22;375(12):1161-70. doi: 10.1056/NEJMra1506330.
5
Clinical Characteristics and Prognosis in Children and Adolescents With Autoimmune Hepatitis and Overlap Syndrome.自身免疫性肝炎和重叠综合征患儿及青少年的临床特征与预后
J Pediatr Gastroenterol Nutr. 2016 Jul;63(1):76-81. doi: 10.1097/MPG.0000000000001125.
6
EASL Clinical Practice Guidelines: Autoimmune hepatitis.欧洲肝脏研究学会临床实践指南：自身免疫性肝炎
J Hepatol. 2015 Oct;63(4):971-1004. doi: 10.1016/j.jhep.2015.06.030. Epub 2015 Sep 1.
7
Overlap syndrome of autoimmune hepatitis and primary sclerosing cholangitis complicated with hepatocellular carcinoma.自身免疫性肝炎与原发性硬化性胆管炎重叠综合征合并肝细胞癌
Clin J Gastroenterol. 2012 Jun;5(3):183-8. doi: 10.1007/s12328-012-0294-5. Epub 2012 Apr 7.
8
NUDT15 R139C causes thiopurine-induced early severe hair loss and leukopenia in Japanese patients with IBD.NUDT15 R139C在日本炎症性肠病患者中导致硫嘌呤诱导的早期严重脱发和白细胞减少。
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9
Risk factors associated with relapse of type 1 autoimmune hepatitis in Japan.与日本 1 型自身免疫性肝炎复发相关的风险因素。
Hepatol Res. 2011 Jul;41(7):641-6. doi: 10.1111/j.1872-034X.2011.00812.x.
10
Diagnosis and management of autoimmune hepatitis.自身免疫性肝炎的诊断与管理
Hepatology. 2010 Jun;51(6):2193-213. doi: 10.1002/hep.23584.