Department of Cardiology, People's Hospital of Deyang City, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Deyang, Sichuan, China.
Department of Cardiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Sci Rep. 2022 Feb 2;12(1):1808. doi: 10.1038/s41598-022-05288-7.
Epidemiological studies have indicated that natural disasters have important impacts on ischemic stroke. This study determined the associations between natural disasters and the incidence and prevalence of ischemic stroke at the global level. A 28-year ecological trend study was performed to estimate worldwide changes in the incidence and prevalence of ischemic stroke and their associations with natural disasters by analyzing data from 193 countries. Quantum geographic information system-based visualization and multivariable linear regression were used. Changes in the incidence and prevalence of ischemic stroke, as well as disaster occurrence, varied among the different regions over the past 28 years (p < 0.001). Multiple linear regression revealed an independent and positive association between disaster occurrence and the incidence of ischemic stroke in males, females and both sexes combined (standardized coefficients = 0.515, 0.470 and 0.483, p < 0.001); similar associations were found for the prevalence of ischemic stroke (standardized coefficients = 0.471, 0.417 and 0.438, p < 0.001). The incidence and prevalence of ischemic stroke changed significantly at the global level and were independently associated with natural disasters. Both males and females show common but different vulnerabilities to natural disasters. This evidence supports policy making and resource allocation for disaster response and disease burden reduction.
流行病学研究表明，自然灾害对缺血性脑卒中具有重要影响。本研究旨在确定全球范围内自然灾害与缺血性脑卒中发病率和患病率之间的关联。通过分析来自 193 个国家的数据，进行了一项为期 28 年的生态学趋势研究，以评估全球范围内缺血性脑卒中发病率和患病率的变化及其与自然灾害的关系。采用基于量子地理信息系统的可视化和多元线性回归方法。过去 28 年，不同地区缺血性脑卒中发病率和患病率以及灾害发生情况的变化存在差异（p<0.001）。多元线性回归显示，在男性、女性和两性人群中，灾害发生与缺血性脑卒中发病率之间存在独立的正相关关系（标准化系数分别为 0.515、0.470 和 0.483，p<0.001）；在缺血性脑卒中患病率方面也存在类似的关联（标准化系数分别为 0.471、0.417 和 0.438，p<0.001）。全球范围内缺血性脑卒中的发病率和患病率发生了显著变化，且与自然灾害独立相关。男性和女性都表现出对自然灾害的共同但不同的脆弱性。这一证据支持制定政策和分配资源，以应对灾害和减轻疾病负担。
