Pediatric Hematology-Oncology, Department of Pediatrics, Saint Joseph's University Medical Center, 703 Main Street, Paterson, NJ, 07503, USA.
Pediatric Hematology-Oncology, Department of Pediatrics, Bronson Methodist Hospital, 601 John Street, Kalamazoo, MI, 49007, USA.
Curr Oncol Rep. 2022 Mar;24(3):295-302. doi: 10.1007/s11912-022-01207-1. Epub 2022 Feb 3.
This study aims to describe what is currently known about how children with cancer have been affected by the COVID-19 pandemic, including morbidity and mortality, interruptions in cancer care and delays in diagnosis, and psychosocial effects. Here we summarize the literature on how this patient population has fared during the pandemic, reviewing multiple smaller reports along with two large registries.
Although children with cancer generally have better outcomes with COVID-19 infection than adults with cancer, their risks of hospitalization, ICU admission, and death are greatly increased compared to the general pediatric population. There are socioeconomic and ethnic disparities present in these effects. Children with cancer experience significant risks from the COVID-19 pandemic. It has yet to be seen how delays and interruptions of cancer treatment and direct organ toxicities caused by the virus itself may affect long-term outcomes in these patients.
本研究旨在描述儿童癌症患者在 COVID-19 大流行期间的患病和死亡情况,癌症治疗中断和诊断延迟,以及心理社会影响等方面的现状。我们对大流行期间这一患者群体的研究进行了总结,综合了多项小型报告和两项大型注册研究。
尽管儿童癌症患者感染 COVID-19 的总体预后优于成人癌症患者,但与普通儿科人群相比,他们住院、入住 ICU 和死亡的风险显著增加。这些影响存在社会经济和种族差异。儿童癌症患者面临着 COVID-19 大流行的严重威胁。目前尚不清楚病毒本身导致的治疗延迟和中断以及直接的器官毒性将如何影响这些患者的长期预后。