Suppr超能文献

儿童癌症患者中的 COVID-19 。

COVID-19 in Children with Cancer.

机构信息

Pediatric Hematology-Oncology, Department of Pediatrics, Saint Joseph's University Medical Center, 703 Main Street, Paterson, NJ, 07503, USA.

Pediatric Hematology-Oncology, Department of Pediatrics, Bronson Methodist Hospital, 601 John Street, Kalamazoo, MI, 49007, USA.

出版信息

Curr Oncol Rep. 2022 Mar;24(3):295-302. doi: 10.1007/s11912-022-01207-1. Epub 2022 Feb 3.

Abstract

PURPOSE OF REVIEW

This study aims to describe what is currently known about how children with cancer have been affected by the COVID-19 pandemic, including morbidity and mortality, interruptions in cancer care and delays in diagnosis, and psychosocial effects. Here we summarize the literature on how this patient population has fared during the pandemic, reviewing multiple smaller reports along with two large registries.

RECENT FINDINGS

Although children with cancer generally have better outcomes with COVID-19 infection than adults with cancer, their risks of hospitalization, ICU admission, and death are greatly increased compared to the general pediatric population. There are socioeconomic and ethnic disparities present in these effects. Children with cancer experience significant risks from the COVID-19 pandemic. It has yet to be seen how delays and interruptions of cancer treatment and direct organ toxicities caused by the virus itself may affect long-term outcomes in these patients.

摘要

目的综述

本研究旨在描述儿童癌症患者在 COVID-19 大流行期间的患病和死亡情况,癌症治疗中断和诊断延迟,以及心理社会影响等方面的现状。我们对大流行期间这一患者群体的研究进行了总结,综合了多项小型报告和两项大型注册研究。

最近发现

尽管儿童癌症患者感染 COVID-19 的总体预后优于成人癌症患者,但与普通儿科人群相比,他们住院、入住 ICU 和死亡的风险显著增加。这些影响存在社会经济和种族差异。儿童癌症患者面临着 COVID-19 大流行的严重威胁。目前尚不清楚病毒本身导致的治疗延迟和中断以及直接的器官毒性将如何影响这些患者的长期预后。

相似文献

1
COVID-19 in Children with Cancer.
Curr Oncol Rep. 2022 Mar;24(3):295-302. doi: 10.1007/s11912-022-01207-1. Epub 2022 Feb 3.
2
Characterization of COVID-19 disease in pediatric oncology patients: The New York-New Jersey regional experience.
Pediatr Blood Cancer. 2021 Mar;68(3):e28843. doi: 10.1002/pbc.28843. Epub 2020 Dec 18.
3
Characteristics in Pediatric Patients with Coronavirus Disease 2019 in Korea.
J Korean Med Sci. 2021 May 24;36(20):e148. doi: 10.3346/jkms.2021.36.e148.
5
7
The Care of Children With Cancer During the COVID-19 Pandemic.
Am Soc Clin Oncol Educ Book. 2021 Mar;41:1-10. doi: 10.1200/EDBK_321497.
8
COVID-19 in cancer patients: clinical characteristics and outcome-an analysis of the LEOSS registry.
Ann Hematol. 2021 Feb;100(2):383-393. doi: 10.1007/s00277-020-04328-4. Epub 2020 Nov 7.
9
SARS-CoV-2 in children with cancer in Brazil: Results of a multicenter national registry.
Pediatr Blood Cancer. 2021 Dec;68(12):e29223. doi: 10.1002/pbc.29223. Epub 2021 Jul 20.

引用本文的文献

2
The quantity and quality of B-cell immunity against SARS-CoV-2 in children with cancer and hematological diseases.
Front Immunol. 2025 Jul 2;16:1613778. doi: 10.3389/fimmu.2025.1613778. eCollection 2025.
4
Clinical Outcomes of Pediatric Cancer Patients with COVID-19: A Cross-Sectional Study.
Int J Hematol Oncol Stem Cell Res. 2024 Oct 1;18(4):313-322. doi: 10.18502/ijhoscr.v18i4.16756.
5
The Impact of COVID-19 on Children and Adolescents with Chronic Illness.
Adv Exp Med Biol. 2024;1457:385-399. doi: 10.1007/978-3-031-61939-7_22.
6
Factors impacting physical activity among post-treatment pediatric cancer survivors with overweight and obesity.
Eur J Pediatr. 2024 Jul;183(7):3129-3136. doi: 10.1007/s00431-024-05584-6. Epub 2024 Apr 26.
8
COVID-19 in Pediatric Patients With Acute Lymphoblastic Leukemia or Lymphoma.
JAMA Netw Open. 2024 Feb 5;7(2):e2355727. doi: 10.1001/jamanetworkopen.2023.55727.
9
10
Global caregiver perspectives on COVID-19 immunization in childhood cancer: A qualitative study.
Front Public Health. 2023 Mar 7;11:1004263. doi: 10.3389/fpubh.2023.1004263. eCollection 2023.

本文引用的文献

1
Hospitalizations Associated with COVID-19 Among Children and Adolescents - COVID-NET, 14 States, March 1, 2020-August 14, 2021.
MMWR Morb Mortal Wkly Rep. 2021 Sep 10;70(36):1255-1260. doi: 10.15585/mmwr.mm7036e2.
2
Global characteristics and outcomes of SARS-CoV-2 infection in children and adolescents with cancer (GRCCC): a cohort study.
Lancet Oncol. 2021 Oct;22(10):1416-1426. doi: 10.1016/S1470-2045(21)00454-X. Epub 2021 Aug 26.
3
The BNT162b2 mRNA COVID-19 vaccine in adolescents and young adults with cancer: A monocentric experience.
Eur J Cancer. 2021 Sep;154:30-34. doi: 10.1016/j.ejca.2021.06.002. Epub 2021 Jun 23.
4
COVID-19 infection in children with underlying malignancies in Iran.
J Basic Clin Physiol Pharmacol. 2021 Jul 1;33(1):79-84. doi: 10.1515/jbcpp-2021-0057.
5
Delayed diagnosis and treatment of children with cancer during the COVID-19 pandemic.
Int J Clin Oncol. 2021 Aug;26(8):1569-1574. doi: 10.1007/s10147-021-01971-3. Epub 2021 Jun 18.
6
COVID-19 outcomes in a large pediatric hematology-oncology center in Houston, Texas.
Pediatr Hematol Oncol. 2021 Nov;38(8):695-706. doi: 10.1080/08880018.2021.1924327. Epub 2021 May 25.
10
Impact of COVID-19 on the Children with Cancer in Six Pediatric Oncology Units (POUs) of Pakistan- A Multi-Center Study.
Cancer Invest. 2022 May;40(5):401-405. doi: 10.1080/07357907.2021.1916027. Epub 2022 Apr 6.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验