Department of Psychosomatic Medicine and Psychotherapy, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Institute of Human Genetics, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany; Insitute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Wilhelm-Johnen-Straße, Jülich, Germany; Centre for Human Genetics, University of Marburg, Baldingerstraße, 35033, Marburg, Germany.
J Psychiatr Res. 2022 Mar;147:283-290. doi: 10.1016/j.jpsychires.2022.01.019. Epub 2022 Jan 12.
Individuals with social anxiety disorder (SAD) often suffer from comorbid major depressive disorder (MDD), which goes along with increased clinical and functional impairment. There has been little research on underlying differences regarding childhood adversities and attachment styles between individuals with SAD with and without comorbid MDD. In the present study, the consecutive sample comprised 612 SCID-diagnosed participants. Of these, n = 472 (62.3% women, 40.7 ± 13.8 years) showed SAD and comorbid MDD (SAD-MDD group) and n = 140 (47.9% women, 43.7 ± 14.7 years) showed just SAD (SAD group). The two groups were compared regarding SAD symptom severity (Social Phobia Inventory; SPIN), childhood adversities (Adverse Childhood Experience Questionnaire; ACE) and attachment styles (Attachment Style Questionnaire, ASQ). The SAD-MDD group reported significantly more severe SAD symptoms (p = .002, d = 0.30), more childhood adversities (p < .001, d = 0.35) and a higher level of fearful attachment style (p < .001, d = 0.30). Group significantly moderated the association between fearful attachment style and SAD symptom severity (β = .292, p < .05) but not between preoccupied attachment style and SAD symptom severity (β = -.184, p = .124; R = .168, p < .05). Fearful attachment style mediated the association between childhood adversities and SAD symptom severity in the SAD-MDD group. Our study could identify a specific significance of fearful attachment style for the association between negative childhood experiences and social anxiety symptoms in SAD-MDD. Findings have specific implications for the therapeutic relationship.
社交焦虑障碍(SAD)患者常伴有共病的重度抑郁症(MDD),这会导致更严重的临床和功能损害。然而,针对 SAD 患者中是否存在伴或不伴共病 MDD 者在童年逆境和依恋风格方面的潜在差异,目前研究较少。本研究采用连续样本,包含 612 名 SCID 诊断的参与者。其中,n = 472 名(62.3%为女性,年龄 40.7 ± 13.8 岁)患有 SAD 合并 MDD(SAD-MDD 组),n = 140 名(47.9%为女性,年龄 43.7 ± 14.7 岁)患有单纯 SAD(SAD 组)。比较了两组的 SAD 症状严重程度(社交恐惧症量表;SPIN)、童年逆境(童年不良经历问卷;ACE)和依恋风格(依恋风格问卷,ASQ)。SAD-MDD 组报告的 SAD 症状严重程度明显更严重(p =.002,d = 0.30),童年逆境经历更多(p <.001,d = 0.35),且恐惧型依恋风格水平更高(p <.001,d = 0.30)。依恋风格分组显著调节了恐惧型依恋风格与 SAD 症状严重程度之间的关联(β =.292,p <.05),但调节了未解决型依恋风格与 SAD 症状严重程度之间的关联(β = -.184,p =.124;R 2 =.168,p <.05)。在 SAD-MDD 组中,恐惧型依恋风格在童年逆境与 SAD 症状严重程度之间起中介作用。本研究确定了恐惧型依恋风格对 SAD-MDD 患者中消极的童年经历与社交焦虑症状之间关联的特定意义。研究结果对治疗关系具有特定的启示。