Klinik für Kinder- und Jugendmedizin, Städtisches Krankenhaus Kiel, Kiel, Germany.
Abteilung Pädiatrische Pneumologie, Allergologie und CF-Zentrum, Universitätskinderklinik Bochum, Bochum, Germany.
Klin Padiatr. 2022 Sep;234(5):257-266. doi: 10.1055/a-1727-5895. Epub 2022 Feb 3.
This narrative review sums up data from the SARS-CoV-2-pandemia on preexisting disease/underlying conditions/comorbidities and risk factors in children for severe COVID-19 and MIS-C/PIMS-TS as well as hospitalization and mortality. Young infants and adolescents are at highest risk of hospital and PICU admission. Two or more comorbidities rather than single entities pose a risk for more severe courses of SARS-CoV-2 infection in children. Asthma and malignancy do not increase complication rates. MIS-C/PIMS-TS is not associated with any specific underlying disease.
这篇叙述性综述总结了 SARS-CoV-2 大流行期间有关儿童重症 COVID-19 和 MIS-C/PIMS-TS 以及住院和死亡率的基础疾病/合并症和危险因素的数据。小婴儿和青少年住院和入住 PICU 的风险最高。两种或多种合并症而不是单一实体使儿童 SARS-CoV-2 感染更严重的风险增加。哮喘和恶性肿瘤不会增加并发症发生率。MIS-C/PIMS-TS 与任何特定的基础疾病无关。
