Mathur Purva, Mittal Samarth, Trikha Vivek, Srivastav Sharad, Pandey R M, Katyal Sonal, Singh Parul, Khurana Surbhi, Malhotra Rajesh, Walia Kamini
Department of Laboratory Medicine, JPNA Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.
Department of Orthopedics, JPNA Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.
Indian J Med Microbiol. 2022 Apr-Jun;40(2):268-273. doi: 10.1016/j.ijmmb.2021.12.016. Epub 2022 Feb 1.
Surgical site infections (SSIs) are one of the most common, causing substantial morbidity, mortality and are highly cost-effective means of reducing healthcare associated infections rates in health care set-ups. In India, there is no existing system for systematic surveillance of SSIs, encompassing post-discharge period.
An indigenous SSI e-surveillance software was developed. Patients developing SSI as per standard definitions were included in the study. A denominator form and a case report form were filled for each case of SSI detected. The microbiological diagnosis was done as per standard methods. Logistic regression analysis was used to test for association of SSI and risk factors and determining the prevalence odds ratios.
Of the total of 850 patients enrolled in the SSI surveillance, 47 (5.5%) developed SSI. Most patients (490/850, 58%) underwent the open reduction internal fixation (ORIF) and also developed an SSI (33/490, 6.7%). Clean contaminated wound class and Dressing were found to be associated with increased risk of SSI significantly, Also increase in the length of stay was found to be associated with increased risk of SSI significantly. High antimicrobial resistance was observed in the microbial isolates recovered from SSIs. Patients who developed SSI had longer hospital stays.
Our study has been the first systematic surveillance effort in India, where patients were followed up till six months post surgeries. This pilot study was later expanded to other Indian hospitals. This network of SSI-Surveillance will lay the foundation for initiation of SSI-surveillance across the country.
手术部位感染(SSIs)是最常见的感染之一,会导致严重的发病和死亡,并且是降低医疗机构中与医疗保健相关感染率的高成本效益手段。在印度,尚无涵盖出院后时期的系统性手术部位感染监测系统。
开发了一种本土的手术部位感染电子监测软件。根据标准定义发生手术部位感染的患者被纳入研究。为每例检测到的手术部位感染病例填写一份分母表格和一份病例报告表格。微生物诊断按照标准方法进行。使用逻辑回归分析来检验手术部位感染与危险因素的关联,并确定患病率比值比。
在纳入手术部位感染监测的850例患者中,有47例(5.5%)发生了手术部位感染。大多数患者(490/850,58%)接受了切开复位内固定术(ORIF),并且也发生了手术部位感染(33/490,6.7%)。发现清洁 - 污染伤口类别和换药与手术部位感染风险显著增加相关,住院时间延长也与手术部位感染风险显著增加相关。从手术部位感染中分离出的微生物菌株观察到高耐药性。发生手术部位感染的患者住院时间更长。
我们的研究是印度首次进行的系统性监测工作,对患者进行了长达术后六个月的随访。这项试点研究后来扩展到了其他印度医院。这个手术部位感染监测网络将为在全国范围内开展手术部位感染监测奠定基础。