Applebaum D, Halperin E
Am J Emerg Med. 1986 Mar;4(2):143-5. doi: 10.1016/0735-6757(86)90160-9.
Lidocaine is one of the most frequently used drugs to suppress ventricular arrhythmias; however, it has caused sinus arrest when given in excess or along with other antiarrhythmics (quinidine, phenytoin, amiodorane). A case of asystole after a conventional dose of lidocaine and resuscitation following discontinuance is reported. Although such complications are rare, the widespread utilization of this drug requires emergency physicians to recognize the potential for this problem.
利多卡因是最常用于抑制室性心律失常的药物之一;然而,过量使用或与其他抗心律失常药物(奎尼丁、苯妥英、胺碘酮)合用时,可导致窦性停搏。本文报告1例常规剂量利多卡因使用后出现心搏停止,停药后复苏成功的病例。尽管此类并发症罕见,但由于该药物广泛应用,急诊医生需认识到这一潜在问题。