Speake B K, Parkin S M, Robinson D S
Biochim Biophys Acta. 1986 Mar 19;881(1):155-7. doi: 10.1016/0304-4165(86)90109-1.
The incorporation of [3H]leucine into lipoprotein lipase during incubations of rat epididymal fat-bodies in vitro was significantly stimulated by dexamethasone, whereas total protein synthesis was unaffected. The stimulation by dexamethasone required the presence of insulin. The results suggest that dexamethasone, in the presence of insulin, may specifically induce lipoprotein lipase synthesis in adipose tissue.
在体外培养大鼠附睾脂肪体的过程中,地塞米松显著刺激了[3H]亮氨酸掺入脂蛋白脂肪酶,而总蛋白质合成未受影响。地塞米松的刺激作用需要胰岛素的存在。结果表明,在胰岛素存在的情况下,地塞米松可能特异性诱导脂肪组织中脂蛋白脂肪酶的合成。