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肾移植 1 年后的移植肾功能。

Kidney graft functionality 1 year after kidney transplantation.

机构信息

Unidad de Investigación Médica en Enfermedades Nefrológicas, Hospital de Especialidades Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS).

Unidad de Trasplante Renal, Hospital de Especialidades Centro Médico Nacional Siglo XXI, IMSS.

出版信息

Cir Cir. 2022;90(1):90-99. doi: 10.24875/CIRU.20001011.

Abstract

OBJECTIVE

To determine the evolution, associated factors and the outcomes of transplanted people one year after the evolution of a cohort in Mexico.

METHOD

Kidney transplant cohort from 2013 to 2017 in Mexico. 1118 patients were analyzed. Five outcomes were studied: overall survival, kidney graft, patient survival, delayed function, and acute dysfunction. Kaplan-Meier was used for kidney graft survival. For risk, bivariate and multivariate analyzes were performed with a significant value of p < 0.05.

RESULTS

Of the 1118 kidney transplant patients, 57 (5.09%) had kidney graft loss, 52 (4.65%) died during the one-year follow-up; survival of the patient of 95.35% and of the graft 90.25%.

CONCLUSIONS

The risk factors for the outcomes were transplantation from a deceased donor, recipient over 50 years of age and use of polyclonal agents. Infections and age are related to the death of the patient.

摘要

目的

确定墨西哥一个队列演变一年后移植患者的演变、相关因素和结局。

方法

对 2013 年至 2017 年墨西哥的肾移植队列进行了分析,共分析了 1118 名患者。研究了 5 个结局:总生存率、肾移植物生存率、患者生存率、延迟功能和急性功能障碍。使用 Kaplan-Meier 法评估肾移植物生存率。对风险因素进行了单变量和多变量分析,p 值<0.05 为有统计学意义。

结果

在 1118 例肾移植患者中,有 57 例(5.09%)发生肾移植物丢失,52 例(4.65%)在一年随访期间死亡;患者生存率为 95.35%,移植物生存率为 90.25%。

结论

结局的危险因素包括来自已故供体的移植、受体年龄超过 50 岁和使用多克隆制剂。感染和年龄与患者死亡有关。

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