Athow A C, Lewin M R, Sewerniak A T, Clark C G
Br J Surg. 1986 Feb;73(2):132-5. doi: 10.1002/bjs.1800730220.
Modified sham feeding (MSF) and insulin tests were carried out in 28 patients after vagotomy. Basal and pentagastrin collections were also performed. Using the secretory data from 9 of the patients with endoscopically proven recurrent ulcer as a reference, 20 gastric secretory indices were studied and critical levels were chosen to provide the maximum sensitivity and specificity. The eleven most discriminating indices were then used to evaluate the remaining 19 patients. There was agreement between the responses to MSF and insulin as to the adequacy of vagotomy in 16 of the patients (84 per cent) and contradictory responses in 3 patients (16 per cent). Overall, MSF responses were as discriminating as the responses to insulin. A simplified ward test, based on crude volume measurements in response to MSF is proposed.
对28例迷走神经切断术后患者进行了改良假饲(MSF)和胰岛素试验。同时也进行了基础胃酸分泌和五肽胃泌素刺激后的胃酸分泌收集。以内镜证实有复发性溃疡的9例患者的分泌数据作为参考,研究了20项胃分泌指标,并选择临界值以提供最大的敏感性和特异性。然后使用11项最具鉴别力的指标对其余19例患者进行评估。16例患者(84%)对MSF和胰岛素的反应在迷走神经切断是否充分方面是一致的,3例患者(16%)存在矛盾反应。总体而言,MSF反应与胰岛素反应具有相同的鉴别力。提出了一种基于对MSF反应的粗略容量测量的简化病房试验。