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本文引用的文献

1
Are Financial Payments From the Pharmaceutical Industry Associated With Physician Prescribing? : A Systematic Review.制药业的财务支付与医生处方是否有关?:系统评价。
Ann Intern Med. 2021 Mar;174(3):353-361. doi: 10.7326/M20-5665. Epub 2020 Nov 24.
2
Association between industry payments for opioid products and physicians' prescription of opioids: observational study with propensity-score matching.工业界为阿片类产品支付款项与医生开具阿片类药物处方之间的关联:倾向评分匹配的观察性研究。
J Epidemiol Community Health. 2020 Aug;74(8):647-654. doi: 10.1136/jech-2020-214021. Epub 2020 Apr 29.
3
Assessment of Expected Out-of-Pocket Spending for Rheumatoid Arthritis Biologics Among Patients Enrolled in Medicare Part D, 2010-2019.2010-2019 年医疗保险部分 D 计划中类风湿关节炎生物制剂患者自付费用预期评估。
JAMA Netw Open. 2020 Apr 1;3(4):e203969. doi: 10.1001/jamanetworkopen.2020.3969.
4
Older Drugs With Limited Trial Evidence: Are They Worth the Expense?试验证据有限的老药:它们值得花费这笔钱吗?
Ann Intern Med. 2019 Oct 15;171(8):602. doi: 10.7326/L19-0520.
5
Association of Pharmaceutical Industry Marketing of Opioid Products to Physicians With Subsequent Opioid Prescribing.制药行业向医生推销阿片类产品与随后的阿片类药物处方之间的关联。
JAMA Intern Med. 2018 Jun 1;178(6):861-863. doi: 10.1001/jamainternmed.2018.1999.
6
2015 American College of Rheumatology Workforce Study: Supply and Demand Projections of Adult Rheumatology Workforce, 2015-2030.2015 年美国风湿病学会劳动力研究:2015-2030 年成人风湿病劳动力的供应和需求预测。
Arthritis Care Res (Hoboken). 2018 Apr;70(4):617-626. doi: 10.1002/acr.23518.
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National Health Care Spending In 2016: Spending And Enrollment Growth Slow After Initial Coverage Expansions.2016 年国家医疗保健支出:在最初的覆盖范围扩大后,支出和参保人数增长放缓。
Health Aff (Millwood). 2018 Jan;37(1):150-160. doi: 10.1377/hlthaff.2017.1299. Epub 2017 Dec 6.
8
Association between payments from manufacturers of pharmaceuticals to physicians and regional prescribing: cross sectional ecological study.制药厂商向医生支付款项与地区处方之间的关联:横断面生态研究。
BMJ. 2016 Aug 18;354:i4189. doi: 10.1136/bmj.i4189.
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Physician-Industry Interactions and Anti-Vascular Endothelial Growth Factor Use Among US Ophthalmologists.美国眼科医生的医患行业互动与抗血管内皮生长因子药物的使用情况
JAMA Ophthalmol. 2016 Aug 1;134(8):897-903. doi: 10.1001/jamaophthalmol.2016.1678.
10
Pharmaceutical Industry-Sponsored Meals and Physician Prescribing Patterns for Medicare Beneficiaries.制药业赞助的餐饮与医疗保险受益人的医师处方模式
JAMA Intern Med. 2016 Aug 1;176(8):1114-1122. doi: 10.1001/jamainternmed.2016.2765.

制药商支付款项与风湿病学处方行为之间的关联。

Association Between Payments by Pharmaceutical Manufacturers and Prescribing Behavior in Rheumatology.

机构信息

Division of Rheumatology, Department of Medicine, Mayo Clinic, Rochester, MN; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN.

Division of Rheumatology, Department of Medicine, Mayo Clinic, Rochester, MN; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.

出版信息

Mayo Clin Proc. 2022 Feb;97(2):250-260. doi: 10.1016/j.mayocp.2021.08.026.

DOI:10.1016/j.mayocp.2021.08.026
PMID:35120693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9013005/
Abstract

OBJECTIVE

To evaluate the association between pharmaceutical industry payments to rheumatologists and their prescribing behaviors.

METHODS

A cross-sectional analysis was conducted of Medicare Part B Public Use File, Medicare Part D Public Use File, and Open Payments data for 2013 to 2015. Prescription drugs responsible for 80% of the total Medicare pharmaceutical expenditures in rheumatology were analyzed. We calculated the mean annual drug cost per beneficiary per year, the percentage of rheumatologists who received payments, and the median annual payment per physician per drug per year. Industry payments were categorized as food/beverage and consulting/compensation. Multivariable regression models were used to assess associations between industry payments and both prescribing patterns and prescription drug expenditures.

RESULTS

Of 4822 rheumatologists in the Medicare prescribing databases, 3729 received any payment from a pharmaceutical company during this time frame. Food/beverage payments were associated with an increased proportion of prescriptions for the related drugs (range, 1.5% to 4.5%) and an increased proportion of annual Medicare spending for the related drugs (range, 3% to 23%). For every $100 in food/beverage payments, the probability of prescribing increased (range, 1.5% to 14% for most drugs) and Medicare reimbursements increased (range, 6% to 44% for most drugs). Consulting/compensation payments were associated with an increased proportion of prescriptions (range, 1.2% to 1.6%) and an increased proportion of annual Medicare spending (range, 1% to 2%). For every $1000 in consulting/compensation payments, both the probability of prescribing increased (5% or less for most drugs) and Medicare reimbursements increased (less than 10% for most drugs).

CONCLUSION

Payments to rheumatologists by pharmaceutical companies are associated with increased probability of prescribing and Medicare spending.

摘要

目的

评估制药业向风湿病学家支付款项与其处方行为之间的关联。

方法

对 2013 年至 2015 年医疗保险 B 部分公共使用文件、医疗保险 D 部分公共使用文件和公开支付数据进行了横断面分析。分析了在风湿病学中占医疗保险药品总支出 80%的处方药。我们计算了每位受益人的平均年药物费用、收到付款的风湿病学家的百分比以及每位医生每种药物的年平均付款。行业付款分为食品/饮料和咨询/补偿。使用多变量回归模型评估行业支付与处方模式和处方药支出之间的关联。

结果

在医疗保险处方数据库中的 4822 名风湿病学家中,有 3729 名在这段时间内从制药公司收到任何款项。食品/饮料付款与相关药物的处方比例增加(范围为 1.5%至 4.5%)以及相关药物的年度医疗保险支出比例增加(范围为 3%至 23%)有关。对于每 100 美元的食品/饮料付款,开处方的可能性增加(大多数药物的范围为 1.5%至 14%),医疗保险报销增加(大多数药物的范围为 6%至 44%)。咨询/补偿付款与处方比例增加(范围为 1.2%至 1.6%)和年度医疗保险支出比例增加(范围为 1%至 2%)有关。对于每 1000 美元的咨询/补偿付款,开处方的可能性增加(大多数药物为 5%或更少),医疗保险报销增加(大多数药物不到 10%)。

结论

制药公司向风湿病学家支付款项与开处方的可能性增加和医疗保险支出增加有关。