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提上睑肌切除术治疗单纯性先天性上睑下垂:对术前提上睑肌功能的影响及剂量反应比。

Levator muscle resection for simple congenital ptosis: its impact on preoperative levator function and dose-response ratio.

机构信息

Department of Ophthalmology, Nikookari Eye Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

Department of Ophthalmology, Nikookari Eye Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Can J Ophthalmol. 2023 Jun;58(3):235-238. doi: 10.1016/j.jcjo.2022.01.008. Epub 2022 Feb 2.

Abstract

OBJECTIVE

The primary aim of this study is to calculate the dose-response ratio in patients with different levels of levator function following levator resection in simple congenital ptosis. The secondary outcome is to evaluate the success rate and effect of levator resection on postoperative levator function.

METHODS

In a retrospective study, the medical records of patients were reviewed for age, gender, laterality, preoperative and postoperative measurements (palpebral fissure height, marginal reflex distance 1, and levator function), magnitude of levator resection, follow-up time, and postoperative complications.

RESULTS

Of 154 patients with a mean age of 17.12 ± 11.14 years, 54 patients had excellent levator function, 41 had good function, and 59 had fair function. Following surgery, the mean levator function increased from 8.81 ± 3.40 mm to 11.29 ± 3.25 mm. The magnitude of increase in the 3 groups of excellent, good, and fair was 3.18 ± 2.63, 2.53 ± 2.24 and 1.92 ± 1.80 mm, respectively. The rate of success was 81.8% with no statistically significant difference in the 3 groups. In a multivariate logistic regression, older age, local anaesthesia, and milder ptosis were predictors of success. A table of dose-response ratios was calculated that determined the amounts of levator muscle resection for 1 mm of marginal reflex distance 1 and levator function increase.

CONCLUSIONS

Levator resection has high success rate in patients with simple congenital ptosis. The function of levator muscle improved significantly following surgery, and the rate of improvement was higher in patients with better preoperative levator function.

摘要

目的

本研究的主要目的是计算单纯性先天性上睑下垂提肌切除术后不同提肌功能水平患者的剂量反应比。次要结果是评估提肌切除术后对术后提肌功能的成功率和效果。

方法

在回顾性研究中,回顾了患者的病历,包括年龄、性别、侧别、术前和术后测量值(睑裂高度、边缘反射距离 1 和提肌功能)、提肌切除量、随访时间和术后并发症。

结果

在 154 例平均年龄为 17.12±11.14 岁的患者中,54 例提肌功能优秀,41 例功能良好,59 例功能一般。手术后,平均提肌功能从 8.81±3.40mm 增加到 11.29±3.25mm。优秀、良好和一般 3 组的增加幅度分别为 3.18±2.63mm、2.53±2.24mm 和 1.92±1.80mm。成功率为 81.8%,3 组间无统计学差异。多元逻辑回归显示,年龄较大、局部麻醉和较轻的上睑下垂是成功的预测因素。计算了剂量反应比表,确定了增加 1mm 边缘反射距离 1 和提肌功能所需的提肌切除量。

结论

单纯性先天性上睑下垂患者行提肌切除术成功率高。术后提肌功能明显改善,术前提肌功能较好的患者改善率更高。

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