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基于κ-卡拉胶和姜黄素-β-环糊精复合物的光动力抗菌膜的综合性能。

Comprehensive properties of photodynamic antibacterial film based on κ-Carrageenan and curcumin-β-cyclodextrin complex.

机构信息

College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, People's Republic of China.

Institute for Medical Research, Ministry of Health Malaysia, Jalan Pahang, 50588 Kuala Lumpur, Malaysia.

出版信息

Carbohydr Polym. 2022 Apr 15;282:119112. doi: 10.1016/j.carbpol.2022.119112. Epub 2022 Jan 10.

Abstract

In this study, a biodegradable photodynamic antibacterial film (Car-Cur) was prepared using casting method with κ-Carrageenan (κ-Car) as film-forming substrate and curcumin-β-cyclodextrin (Cur-β-CD) complex as photosensitizer. The comprehensive performance of this Car-Cur film was investigated. The obtained results showed that the concentration of Cur-β-CD was an important factor determining the properties of film including tensile strength (TS) elongation at break (EB), water vapor permeability (WVP), water content (WC) and thermal stability. When the concentration of Cur-β-CD is 1%, the film demonstrated the maximum TS and EB, increased thermal stability, with desirable WVP and WC. Furthermore, this film also showed good photodynamic antibacterial potential against Staphylococcus aureus and Escherichia coli upon irradiation of blue LED light. Moreover, the film can be degraded in the soil in one week. In conclusion, our results suggested Car-Cur photodynamic film could be developed as biodegradable antimicrobial packaging material for food preservation.

摘要

在这项研究中,采用浇铸法制备了一种可生物降解的光动力抗菌膜(Car-Cur),以κ-卡拉胶(κ-Car)为成膜基质,姜黄素-β-环糊精(Cur-β-CD)复合物为光敏剂。研究了这种 Car-Cur 膜的综合性能。结果表明,Cur-β-CD 的浓度是决定膜性能的重要因素,包括拉伸强度(TS)、断裂伸长率(EB)、水蒸气透过率(WVP)、水分含量(WC)和热稳定性。当 Cur-β-CD 的浓度为 1%时,膜具有最大的 TS 和 EB,提高了热稳定性,同时具有理想的 WVP 和 WC。此外,该膜在蓝光 LED 照射下对金黄色葡萄球菌和大肠杆菌表现出良好的光动力抗菌潜力。此外,该膜可在一周内在土壤中降解。总之,我们的研究结果表明,Car-Cur 光动力抗菌膜可作为可生物降解的抗菌包装材料用于食品保鲜。

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