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Induction of donor-specific tolerance to heart transplantation: From concept to clinical translation.

作者信息

Kang Lillian, Markert M Louise, Turek Joseph W

机构信息

Department of Surgery, Duke University, Durham, NC; Duke Congenital Heart Research & Training Laboratory, Duke University, Durham, NC.

Department of Pediatrics, Duke University Medical Center, Durham, NC; Department of Immunology, Duke University Medical Center, Durham, NC.

出版信息

J Thorac Cardiovasc Surg. 2023 May;165(5):1661-1666. doi: 10.1016/j.jtcvs.2021.12.048. Epub 2022 Jan 14.

DOI:10.1016/j.jtcvs.2021.12.048
PMID:35123789
Abstract
摘要

相似文献

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Induction of donor-specific tolerance to heart transplantation: From concept to clinical translation.诱导心脏移植供体特异性耐受：从概念到临床转化。
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Role of regulatory T cells in CD47/donor-specific transfusion-induced immune tolerance in skin-heart transplantation mice.调节性T细胞在皮肤-心脏移植小鼠中CD47/供体特异性输血诱导的免疫耐受中的作用
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Induction of donor-specific tolerance to rat cardiac allografts by intrathymic inoculation of bone marrow.通过胸腺内接种骨髓诱导对大鼠心脏同种异体移植物的供体特异性耐受。
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Cultured thymus tissue implantation promotes donor-specific tolerance to allogeneic heart transplants.体外培养胸腺组织移植促进供者特异性对同种异体心脏移植的免疫耐受。
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Commentary: Donor-specific tolerance in heart transplantation: A marathon, not a sprint.
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Heart and en-bloc thymus transplantation in miniature swine.小型猪心脏和整块胸腺移植
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The induction of transplantation tolerance by intrathymic (i.t.) delivery of alloantigen: a critical relationship between i.t. deletion, thymic export of new T cells and the timing of transplantation.通过胸腺内（i.t.）给予同种异体抗原诱导移植耐受：胸腺内清除、新T细胞的胸腺输出与移植时机之间的关键关系。
Int Immunol. 1998 Nov;10(11):1637-46. doi: 10.1093/intimm/10.11.1637.
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The effect of thymectomy on tolerance induction and cardiac allograft vasculopathy in a miniature swine heart/kidney transplantation model.胸腺切除术对小型猪心脏/肾脏移植模型中耐受诱导及心脏同种异体移植血管病变的影响。
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Simultaneous transplantation and intrathymic tolerance induction. A method with clinical potential.
Transplantation. 1995 Dec 15;60(11):1208-10.

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Tolerogenic Therapies in Cardiac Transplantation.心脏移植中的耐受性疗法
Int J Mol Sci. 2025 Apr 23;26(9):3968. doi: 10.3390/ijms26093968.
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A novel technique for heart-thymus en bloc transplantation in nonhuman primates.一种用于非人灵长类动物心脏-胸腺整块移植的新技术。
Sci Rep. 2024 Dec 30;14(1):31930. doi: 10.1038/s41598-024-83378-4.
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Consensus statement on heart xenotransplantation in children: Toward clinical translation.儿童心脏异种移植共识声明：迈向临床转化
J Thorac Cardiovasc Surg. 2023 Sep;166(3):960-967. doi: 10.1016/j.jtcvs.2022.09.001. Epub 2022 Sep 6.