Department of Clinical Epidemiology, Office of Clinical Epidemiology, Analytics, and Knowledge, Tan Tock Seng Hospital, Singapore.
Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore; Department of Infection Prevention and Control, Tan Tock Seng Hospital, Singapore.
Int J Infect Dis. 2022 Apr;117:139-145. doi: 10.1016/j.ijid.2022.01.069. Epub 2022 Feb 4.
Following the emergence of the Delta variant of SARS-CoV-2 in Singapore, our hospital experienced a Delta-linked ward cluster. In this study, we review the enhanced strategies in preventing nosocomial transmission of COVID-19 following widespread community transmission of the Delta variant.
We conducted a cohort study on exposures to unexpected COVID-19 cases for which contact tracing was initiated from June 2021 to October 2021. Strategies evaluated included upgraded personal protective equipment (PPE) and rostered routine testing (RRT) for staff and patients, surveillance of staff with acute respiratory illness (ARI), and expanded quarantining and testing for contacts of identified cases.
From 193 unexpected COVID-19 exposures, 2,573 staff, 542 patients, and 128 visitor contacts were traced. Four staff contacts subsequently had SARS-CoV-2 infection. Two were likely from exposure in community settings, whereas 2 had exposure to the same COVID-19 positive staff in the hospital, forming the only hospital cluster. One inpatient had a nosocomial infection, possibly from visitors. The SARS-CoV-2 detection rate among staff was 0.3% (of 11,200 staff) from biweekly RRT and 2.5% (of 3,675 staff) from ARI surveillance.
Enhanced hospital measures, including upgraded PPE and RRT for staff and patients, staff sickness surveillance, and more rigorous management of contacts of COVID-19 cases, were likely to have reduced nosocomial transmission amid the Delta variant.
在新加坡出现 SARS-CoV-2 的 Delta 变异株后,我院出现了与 Delta 变异株相关的病房集群。本研究回顾了在 Delta 变异株广泛社区传播后,为防止 COVID-19 医院内传播而采取的强化策略。
我们对 2021 年 6 月至 2021 年 10 月期间因接触追踪而启动的意外 COVID-19 病例进行了队列研究。评估的策略包括为员工和患者升级个人防护设备(PPE)和常规轮班检测(RRT)、对出现急性呼吸道疾病(ARI)的员工进行监测,以及扩大对已确定病例接触者的隔离和检测。
在 193 例意外 COVID-19 暴露中,共追踪到 2573 名员工、542 名患者和 128 名访客接触者。随后有 4 名员工接触者感染了 SARS-CoV-2。其中 2 人可能是在社区环境中接触的,而另外 2 人是在医院与同一 COVID-19 阳性员工接触的,这是唯一的医院集群。1 名住院患者发生了医院感染,可能是访客导致的。从两周一次的 RRT 中检测到的员工 SARS-CoV-2 检出率为 0.3%(11200 名员工中),从 ARI 监测中检测到的员工 SARS-CoV-2 检出率为 2.5%(3675 名员工中)。
强化医院措施,包括为员工和患者升级 PPE 和 RRT、员工疾病监测以及更严格管理 COVID-19 病例的接触者,可能减少了 Delta 变异株期间的医院内传播。