Faculty of Medicine, Saint Joseph University, Beirut, Lebanon; Hôpital Saint Joseph des Sœurs de la Croix-Centre Médical Raymond et Aida Najjar, Beirut, Lebanon.
Faculty of Medicine, Saint Joseph University, Beirut, Lebanon; Radiology Department, Hôpital Saint Joseph des Sœurs de la Croix-Centre Médical Raymond et Aida Najjar, Beirut, Lebanon.
Clin Imaging. 2022 Apr;84:38-42. doi: 10.1016/j.clinimag.2021.12.009. Epub 2022 Jan 4.
Hypertrophic osteoarthropathy (HOA) is a disease characterized by abnormal skin findings and bone deformities related to subperiosteal bone formation. The disease can be associated with major systemic manifestations (secondary form) or present with absent or less prominent systemic signs and symptoms (primary form). The primary form is called pachydermoperiostosis (PDP). Whole body diffusion weighted imaging with background suppression (WB-DWIBS) is a magnetic resonance imaging (MRI) technique that has been used to highlight whole body involvement in various entities by suppressing background body signals, and is commonly used in oncologic work-ups. In this paper, we present the case of a 23-year-old male presenting with normocytic anemia and coarse facial features, as well as biological anomalies, and we report the use of WB-DWIBS in establishing the patient's diagnosis of PDP.
肥大性骨关节病（HOA）是一种以异常皮肤表现和骨畸形为特征的疾病，与骨膜下骨形成有关。该疾病可伴有主要全身表现（继发性），或表现为全身体征和症状不明显或较轻（原发性）。原发性形式称为厚皮骨膜病（PDP）。全身弥散加权成像背景抑制（WB-DWIBS）是一种磁共振成像（MRI）技术，通过抑制背景身体信号来突出全身各实体的受累情况，常用于肿瘤学检查。本文介绍了一名 23 岁男性患者，表现为正细胞性贫血和粗糙的面部特征，以及生物学异常，并报告了使用 WB-DWIBS 来确立患者 PDP 诊断的情况。
