药用植物的植物化合物对冠状病毒（2019 - NCOV）感染的影响
The Effect of Phytocompounds of Medicinal Plants on Coronavirus (2019-NCOV) Infection.
作者信息
Zrig Ahlem
机构信息
Research Unit of Biodiversity and Valorization of Bioresources in Arid Zones, Faculty of Sciences of Gabès-City Erriadh, 6072 Zrig, Gabes Tunisia.
出版信息
Pharm Chem J. 2022;55(10):1080-1084. doi: 10.1007/s11094-021-02540-8. Epub 2022 Jan 31.
The recent outbreak of coronavirus disease 2019 (COVID-19) is a respiratory infection and it can spread from animal to person, person to person through coughing or physical contact. Recent studies revealed that the genome sequence of this pandemic disease is very similar to that of SARS-CoV, thus, there are not yet effective treatments that target the 2019-nCoV virus. Medicinal plants present a potential solution to resolve the drug problem. In fact, the bioactive compounds such as phenols, flavonoids, monoterpenes, and phenylpropanoids, derived from several herbs such as and could be used to develop formal drugs against several diseases with no or minimal side effects. In this paper, we describe the potential antiviral properties of several medicinal plants against Coronaviridae family viruses such as SARS, MERS, and IBV. Besides, we review various species of medicinal herbs and their derived phytochemical compounds in terms of their immunomodulatory bioactivities and antiviral activity.
近期爆发的2019冠状病毒病（COVID-19）是一种呼吸道感染疾病，它可以从动物传播给人，也可通过咳嗽或身体接触在人与人之间传播。近期研究表明，这种大流行疾病的基因组序列与严重急性呼吸综合征冠状病毒（SARS-CoV）的基因组序列非常相似，因此，目前尚无针对2019新型冠状病毒（2019-nCoV）的有效治疗方法。药用植物为解决药物问题提供了一种潜在的解决方案。事实上，从诸如[此处原文缺失植物名称]等多种草药中提取的酚类、黄酮类、单萜类和苯丙素类等生物活性化合物，可用于开发针对多种疾病且无副作用或副作用极小的正规药物。在本文中，我们描述了几种药用植物对冠状病毒科病毒（如SARS、中东呼吸综合征冠状病毒（MERS）和传染性支气管炎病毒（IBV））的潜在抗病毒特性。此外，我们还综述了各种药用植物及其衍生的植物化学化合物的免疫调节生物活性和抗病毒活性。
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