Agafonov A V, Talygin E A, Bockeria L A, Gorodkov A Yu
Bakulev National Medical Research Center of Cardiovascular Surgery, Ministry of Health of the Russian Federation, Moscow, 121552 Russia.
Acta Naturae. 2021 Oct-Dec;13(4):4-16. doi: 10.32607/actanaturae.11439.
This paper proposes a new approach to the quantitative analysis of the hydrodynamic structure of a blood flow in the flow channel running from the left atrium to the end of the aorta. This approach is based on the concept of the structural organization of tornado-like swirling jets in channels with a given geometric configuration. Considering the large amount of experimental data in our possession, it was shown that along the entire length of the flow channel, conditions exist for the generation and maintenance of a swirling structure of the jet throughout the entire cardiac cycle. This study has given rise to a new direction in research in fundamental physiology and medicine, which is of great practical importance for diagnosing and treating circulatory disorders accompanied by changes in the geometric configuration and biomechanical characteristics of the heart and great vessels.
本文提出了一种新方法,用于对从左心房到主动脉末端的血流通道中的流体动力学结构进行定量分析。该方法基于具有给定几何构型的通道中类似龙卷风的旋流射流的结构组织概念。考虑到我们所拥有的大量实验数据,结果表明,在整个血流通道长度上,在整个心动周期中都存在产生和维持射流旋流结构的条件。这项研究在基础生理学和医学研究中开创了一个新方向,对于诊断和治疗伴有心脏和大血管几何构型及生物力学特性变化的循环系统疾病具有重要的实际意义。