大鼠脑不同区域己糖激酶含量与基础能量代谢的相关性
Correlation of hexokinase content and basal energy metabolism in discrete regions of rat brain.
作者信息
Turek T J, Hawkins R A, Wilson J E
出版信息
J Neurochem. 1986 Mar;46(3):983-5. doi: 10.1111/j.1471-4159.1986.tb13066.x.
Abstract
Brain hexokinase (ATP:D-hexose 6-phosphotransferase, EC 2.7.1.1) levels in seven regions of rat brain were estimated by photometric measurement of immunofluorescence in cryostat-cut sections. When compared with basal rates of glucose metabolism in these regions, estimated by the 6-[14C]glucose method, a significant correlation was observed. Thus, hexokinase content reflects metabolic energy demands.
摘要
通过对冷冻切片中免疫荧光进行光度测量，估算了大鼠大脑七个区域的脑己糖激酶（ATP：D-己糖6-磷酸转移酶，EC 2.7.1.1）水平。当与通过6-[14C]葡萄糖法估算的这些区域的基础葡萄糖代谢率进行比较时，观察到显著相关性。因此，己糖激酶含量反映了代谢能量需求。
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