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Imidazo[2,1-b]benzothiazoles. 2. New immunosuppressive agents.

作者信息

Mase T, Arima H, Tomioka K, Yamada T, Murase K

出版信息

J Med Chem. 1986 Mar;29(3):386-94. doi: 10.1021/jm00153a014.

DOI:10.1021/jm00153a014
PMID:3512827
Abstract

A series of 2-phenylimidazo[2,1-b]benzothiazole derivatives was prepared and tested for immunological activities. Some of the compounds showed significant suppressive activity of delayed type hypersensitivity (DTH) without inhibition of humoral immunity in mice by oral administration. The most active compound was 2-(m-hydroxyphenyl)imidazo[2,1-b]benzothiazole (20).

摘要

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