Ferguson Pamela L, Commodore Sarah, Neelon Brian, Cobbs JacKetta, Sciscione Anthony C, Grobman William A, Newman Roger B, Tita Alan T, Nageotte Michael P, Palomares Kristy, Skupski Daniel W, Vena John E, Hunt Kelly J
Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC.
School of Public Health, Indiana University, Bloomington, IN.
Child Adolesc Obes. 2022;5(1):3-15. doi: 10.1080/2574254x.2021.2021788. Epub 2022 Jan 13.
A few studies have identified childhood animal exposure as associated with adiposity, but results are inconsistent and differ in timing.
We conducted an observational cohort study of children ages 4-8 in the Environmental Influences on Child Health Outcomes [ECHO] study. The main exposure was having a dog in the home and/or regular contact with farm animals during the first year of life. Outcomes of interest were child BMI percentile (adjusted for gender and age) categorized as normal/underweight (<85 percentile), overweight (85 to <95), and obese (≥95), and percent fat mass (continuous). Associations were analyzed using multinomial logistic regression and multivariable linear regression, respectively, with and without multiple imputation.
First year animal exposure occurred in 245 of 770 (31.8%) children. Children with early animal exposure had 0.53 (95% CI: 0.28, 0.997) times the odds of being in the obese BMI category compared to those exposed to animals after controlling for covariates: maternal pre-pregnancy BMI, race/ethnicity, reported child activity level, receiving food assistance, age child began daycare (<1 year vs 1+), exclusively breastfed x6 months, and NICU admission (n=721). Children with early animal exposure had, on average, 1.5% (95% CI: -3.0, -0.1) less fat mass than exposed children after adjustment for maternal BMI, race/ethnicity, activity, food assistance, breastfeeding, and maternal education (n=548). Multiple imputation did not alter either result.
These results provide evidence that exposure to dogs or farm animals in the first year of life is associated with lower odds of obesity and lower percent fat mass in childhood.
一些研究已确定儿童期接触动物与肥胖有关，但结果并不一致，且在时间上存在差异。
我们在环境对儿童健康结果[ECHO]研究中对4至8岁儿童进行了一项观察性队列研究。主要暴露因素是在生命的第一年家中养狗和/或与农场动物有定期接触。感兴趣的结果是儿童BMI百分位数（根据性别和年龄调整），分为正常/体重不足（<85百分位数）、超重（85至<95）和肥胖（≥95），以及体脂百分比（连续变量）。分别使用多项逻辑回归和多变量线性回归分析关联，有无多重填补。
770名儿童中有245名（31.8%）在第一年接触了动物。在控制协变量（母亲孕前BMI、种族/民族、报告的儿童活动水平、接受食品援助、儿童开始日托的年龄（<1岁与1岁以上）、纯母乳喂养6个月以及新生儿重症监护病房入院情况（n = 721））后，早期接触动物的儿童肥胖BMI类别几率是后期接触动物儿童的0.53（95%CI：0.28，0.997）倍。在调整母亲BMI、种族/民族、活动、食品援助、母乳喂养和母亲教育程度后（n = 548），早期接触动物的儿童平均体脂比后期接触动物的儿童少1.5%（95%CI：-3.0，-0.1）。多重填补并未改变任何一个结果。
这些结果表明，生命第一年接触狗或农场动物与儿童期肥胖几率降低和体脂百分比降低有关。
