IVF Unit, Assuta Medical Center, Tel Aviv, Tel-Aviv, Israel.
The Goldman Medical School at the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Reprod Fertil. 2021 Apr 16;2(2):89-94. doi: 10.1530/RAF-20-0064. eCollection 2021 Apr.
Oocyte pick-up (OPU) is a painful but essential part of fertilization (IVF) that is usually performed under sedation and analgesia (SaA). Our aim was to study that why some women decide to undergo OPU without SaA?
This was a prospective study using patient questionnaires and the standardized 7-item generalized anxiety disorder (GAD-7) score. The patients were asked to assess the pain experienced during OPU using a visual analog scale (VAS). The study sample was a convenience sample of 100 healthy women undergoing OPU at our unit with or without SaA.
Women who chose to undergo OPU without SaA were significantly more likely to express the fear of anesthesia. A high pain score (VAS ≥ 6) was reported by significantly more patients who underwent OPU without SaA than with SaA. Yet, 98% of the patients who underwent OPU without SaA stated that in future IVF cycles, they would still choose to undergo OPU without SaA. More patients had high anxiety scores among those who underwent OPU with than without SaA.
Women who chose to undergo OPU without SaA reported more often fear of anesthesia. Although these women experienced significantly more pain during OPU, almost all of them suggested that they would still choose to undergo OPU without SaA. Increased anxiety, as expressed by higher GAD-7 scores, was not associated with a tendency to choose SaA during OPU. The option of OPU without SaA seems to be an acceptable option for selected women.
Egg retrieval from the ovaries is a painful part of fertilization (IVF). It is, therefore, usually performed under sedation and pain relief (analgesia). The aim of this study was to investigate: Why some women decide to undergo egg retrieval without sedation? We prospectively studied 100 women using patient questionnaires and standardized scores in order to measure patient's pain and anxiety levels. We found that women who chose to undergo egg retrieval without sedation were significantly more likely to express fear of anesthesia. As expected, women who decided to forgo sedation experienced more pain during egg retrieval, yet, 98% of them decided that in future IVF cycles, they would still choose to undergo egg retrieval without sedation. Surprisingly, women who had high anxiety scores were not more likely to ask for sedation during egg retrieval. The option to undergo egg retrieval without sedation during IVF seems to be acceptable for some women.
卵母细胞采集（OPU）是受精（IVF）过程中一个痛苦但必不可少的环节，通常在镇静和镇痛（SaA）下进行。我们的目的是研究为什么有些女性决定在没有 SaA 的情况下进行 OPU？
这是一项使用患者问卷调查和标准化的 7 项广泛性焦虑障碍（GAD-7）评分的前瞻性研究。患者被要求使用视觉模拟量表（VAS）评估 OPU 期间的疼痛程度。研究样本是在我们单位接受或不接受 SaA 的 OPU 的 100 名健康女性的便利样本。
选择不接受 SaA 进行 OPU 的女性更有可能表达对麻醉的恐惧。与接受 SaA 进行 OPU 的患者相比，不接受 SaA 进行 OPU 的患者报告的疼痛评分（VAS≥6）明显更高。然而，98%的不接受 SaA 进行 OPU 的患者表示，在未来的 IVF 周期中，他们仍将选择不接受 SaA 进行 OPU。接受 SaA 进行 OPU 的患者中，焦虑评分较高的患者比例明显高于不接受 SaA 进行 OPU 的患者。
选择不接受 SaA 进行 OPU 的女性更频繁地报告对麻醉的恐惧。尽管这些女性在 OPU 期间经历了明显更多的疼痛，但几乎所有女性都表示，她们仍将选择不接受 SaA 进行 OPU。较高的焦虑水平，如较高的 GAD-7 评分所示，与选择在 OPU 期间接受 SaA 无关。不接受 SaA 进行 OPU 的选择似乎是一种可接受的选择，适用于一些女性。
OPU 是受精过程中一个痛苦但必不可少的部分，通常在镇静和镇痛下进行。我们的目的是研究为什么有些女性决定在没有 SaA 的情况下进行 OPU。
这是一项使用患者问卷调查和标准化的 7 项广泛性焦虑障碍（GAD-7）评分的前瞻性研究。患者被要求使用视觉模拟量表（VAS）评估 OPU 期间的疼痛程度。研究样本是在我们单位接受或不接受 SaA 的 OPU 的 100 名健康女性的便利样本。
选择不接受 SaA 进行 OPU 的女性更有可能表达对麻醉的恐惧。与接受 SaA 进行 OPU 的患者相比，不接受 SaA 进行 OPU 的患者报告的疼痛评分（VAS≥6）明显更高。然而，98%的不接受 SaA 进行 OPU 的患者表示，在未来的 IVF 周期中，他们仍将选择不接受 SaA 进行 OPU。接受 SaA 进行 OPU 的患者中，焦虑评分较高的患者比例明显高于不接受 SaA 进行 OPU 的患者。
选择不接受 SaA 进行 OPU 的女性更频繁地报告对麻醉的恐惧。尽管这些女性在 OPU 期间经历了明显更多的疼痛，但几乎所有女性都表示，她们仍将选择不接受 SaA 进行 OPU。较高的焦虑水平，如较高的 GAD-7 评分所示，与选择在 OPU 期间接受 SaA 无关。不接受 SaA 进行 OPU 的选择似乎是一种可接受的选择，适用于一些女性。
