The Nethersole School of Nursing, The Chinese University of Hong Kong, Esther Lee Building, Shatin, Hong Kong SAR, NT, China.
Xiangya School of Nursing, Central South University, Changsha, China.
Support Care Cancer. 2022 Jul;30(7):5615-5626. doi: 10.1007/s00520-022-06881-2. Epub 2022 Feb 7.
Music may be a safe and effective coping strategy for psychological management. The objectives of this review were to identify the effects of music interventions on anxiety, depression, and quality of life (QoL) among cancer patients receiving chemotherapy.
Fourteen databases were searched from the inception date to December 2020 to identify eligible randomized controlled trials (RCTs). Gray literature was also examined. The protocol of this systematic review was registered with PROSPERO (registration number: CRD42021223845). Two reviewers independently assessed eligibility, extracted data, and evaluated methodological quality. Meta-analysis was done. Subgroup analysis was conducted for intervention types, the person selecting music, music delivery method, timing, and session duration.
Nine RCTs were identified, among which six were eligible for the meta-analysis. All studies were at a high risk of bias, and the overall quality of evidence was low to very low. The pooled results reveal that music intervention could reduce anxiety (SMD: - 0.29, 95% CI - 0.50 to - 0.08) and improve QoL (SMD: 0.42, 95% CI 0.02 to 0.82). However, it fails to affect depression (p = 0.79). The findings demonstrate no significant difference between patient-selected music and researcher-selected music, recorded music, and live music, while a length of 15-20 min/session and offering immediately before chemotherapy are more effective on anxiety than that of 30-45 min and delivering during chemotherapy.
Music intervention may be a beneficial tool for anxiety reduction and QoL among cancer patients receiving chemotherapy. More high-quality RCTs are needed to ascertain the true impact of those outcomes.
音乐可能是一种安全有效的心理管理应对策略。本综述的目的是确定音乐干预对接受化疗的癌症患者的焦虑、抑郁和生活质量（QoL）的影响。
从创建日期到 2020 年 12 月，我们检索了 14 个数据库以确定合格的随机对照试验（RCT）。还检查了灰色文献。本系统评价的方案已在 PROSPERO（注册号：CRD42021223845）上注册。两位评审员独立评估合格性、提取数据并评估方法学质量。进行了荟萃分析。进行了干预类型、选择音乐的人员、音乐传递方式、时间和疗程的亚组分析。
确定了 9 项 RCT，其中 6 项符合荟萃分析的条件。所有研究均存在高度偏倚风险，整体证据质量为低至极低。汇总结果表明，音乐干预可以降低焦虑（SMD：-0.29，95%CI：-0.50 至-0.08）和改善 QoL（SMD：0.42，95%CI：0.02 至 0.82）。但是，它对抑郁没有影响（p=0.79）。研究结果表明，患者选择的音乐与研究人员选择的音乐、录制的音乐和现场音乐之间没有显著差异，而 15-20 分钟/疗程和在化疗前立即提供的音乐在缓解焦虑方面比 30-45 分钟和在化疗期间提供的音乐更有效。
音乐干预可能是接受化疗的癌症患者减轻焦虑和提高生活质量的有益工具。需要更多高质量的 RCT 来确定这些结果的真实影响。
