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使用自膨式支架治疗减重手术漏:系统评价和荟萃分析。

Use of self-expandable stents in the treatment of bariatric surgery leaks: a systematic review and meta-analysis.

机构信息

Division of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

出版信息

Gastrointest Endosc. 2012 Feb;75(2):287-93. doi: 10.1016/j.gie.2011.09.010. Epub 2011 Nov 1.

DOI:10.1016/j.gie.2011.09.010
PMID:22047699
Abstract

BACKGROUND

Bariatric surgery leaks can result in significant morbidity and mortality. Endoscopic placement of self-expandable stents (SESs) is emerging as a less-invasive alternative to surgery for the treatment of leaks.

OBJECTIVE

To evaluate the success of SESs in the treatment of bariatric surgery leaks.

DESIGN

Studies using SESs in the management of bariatric surgery leaks were selected. Success of SES treatment was defined as radiographic evidence of leak closure after stent removal. Articles were searched in MEDLINE, PubMed, Ovid, and Cochrane Register of Controlled Trials. Pooled proportions were calculated by using fixed- and random-effects models. Publication bias was calculated by using the Begg-Mazumdar and Harbord bias estimators.

RESULTS

A total of 189 relevant articles were reviewed of which 7 studies (67 patients with leaks) met inclusion criteria. The pooled proportion of successful leak closures by using SESs was 87.77% (95% CI, 79.39%-94.19%). The pooled proportion of successful endoscopic stent removal was 91.57% (95% CI, 84.22%-96.77%). Stent migration was noted in 16.94% (95% CI, 9.32%-26.27%). Test of heterogeneity gave a P value >.10. There was no publication bias.

LIMITATIONS

Small retrospective studies, different types of stents used.

CONCLUSION

Endoscopic placement of SESs is a minimally invasive, safe, and effective alternative in the management of leaks after bariatric surgery. The use of SESs can minimize the need for surgical revision and improve patient outcomes.

摘要

背景

减重手术漏可导致严重的发病率和死亡率。内镜放置自膨式支架(SESs)作为手术治疗漏的一种微创替代方法正在出现。

目的

评估 SESs 治疗减重手术漏的成功率。

设计

选择了使用 SESs 治疗减重手术漏的研究。SES 治疗成功定义为支架取出后漏口影像学证据闭合。在 MEDLINE、PubMed、Ovid 和 Cochrane 对照试验登记处进行了文献检索。使用固定效应和随机效应模型计算了合并比例。使用 Begg-Mazumdar 和 Harbord 偏倚估计器计算了发表偏倚。

结果

共回顾了 189 篇相关文章,其中 7 项研究(67 例漏患者)符合纳入标准。SESs 治疗成功的合并比例为 87.77%(95%CI,79.39%-94.19%)。SES 内镜下支架取出成功率为 91.57%(95%CI,84.22%-96.77%)。支架迁移率为 16.94%(95%CI,9.32%-26.27%)。异质性检验 P 值>0.10。无发表偏倚。

局限性

小回顾性研究,使用不同类型的支架。

结论

内镜下放置 SESs 是治疗减重手术后漏的一种微创、安全、有效的方法。SESs 的使用可以减少手术修复的需要,并改善患者的预后。

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