Cheok Lay Hock, Lee Wendy Wan Hui, Cheng Wee Mee, Cheong Yaw Kiet, Teh Cheng Lay
Department of Internal Medicine, Ministry of Health, 69906Miri Hospital, Miri, Malaysia.
Rheumatology Unit, Department of Internal Medicine, Ministry of Health, 58986Sarawak General Hospital, Kuching, Malaysia.
Lupus. 2022 Mar;31(3):373-377. doi: 10.1177/09612033221078213. Epub 2022 Feb 8.
Aseptic meningitis is a rare presentation of systemic lupus erythematosus (SLE). High index of suspicion is crucial when there is suboptimal response to the initial standard meningitis treatment and presence of connective tissue disease symptoms. We report 3 cases of aseptic meningitis as the main initial presentation of SLE. The diagnosis of SLE as the underlying cause of the aseptic meningitis was supported by the clinical, laboratory and radiological findings. All patients showed good response after treated with immunosuppressant therapy.
无菌性脑膜炎是系统性红斑狼疮（SLE）的一种罕见表现。当对初始标准脑膜炎治疗反应欠佳且存在结缔组织病症状时，高度怀疑至关重要。我们报告3例以无菌性脑膜炎为SLE主要首发表现的病例。临床、实验室及影像学检查结果均支持将SLE诊断为无菌性脑膜炎的潜在病因。所有患者经免疫抑制治疗后均显示出良好疗效。
