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More Evidence for Inflammatory Thrombosis in Chronic Thromboembolic Pulmonary Hypertension: Is the Embolic Hypothesis Losing Ground?慢性血栓栓塞性肺动脉高压中炎症性血栓形成的更多证据:栓塞假说是否正在失势?
Am J Respir Crit Care Med. 2022 Apr 1;205(7):745-746. doi: 10.1164/rccm.202201-0001ED.
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Is pulmonary embolism a common cause of chronic pulmonary hypertension? Limitations of the embolic hypothesis.肺栓塞是慢性肺动脉高压的常见病因吗?栓塞假说的局限性。
Eur Respir J. 2000 Mar;15(3):440-8. doi: 10.1034/j.1399-3003.2000.15.03.x.
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[Chronic pulmonary hypertension caused by left axillary vein thrombosis. Report of a clinical case].[左腋静脉血栓形成所致慢性肺动脉高压。临床病例报告]
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Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2016 Mar;160(1):125-9. doi: 10.5507/bp.2015.021. Epub 2015 May 25.
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[The case of surgically treated severe thromboemboic pulmonary hypertension developing in the course of recurrent pulmonary embolism].[复发性肺栓塞过程中发生的手术治疗严重血栓栓塞性肺动脉高压病例]
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Chronic thromboembolic pulmonary hypertension--not so rare after all.慢性血栓栓塞性肺动脉高压——其实并不那么罕见。
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Consequences of Venous Thromboembolism, Including Chronic Thromboembolic Pulmonary Hypertension.静脉血栓栓塞的后果,包括慢性血栓栓塞性肺动脉高压。
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Prospective cardiopulmonary screening program to detect chronic thromboembolic pulmonary hypertension in patients after acute pulmonary embolism.前瞻性心肺筛查计划以在急性肺栓塞后患者中检测慢性血栓栓塞性肺动脉高压。
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Advances in understanding the pathogenesis of chronic thromboembolic pulmonary hypertension.深入了解慢性血栓栓塞性肺动脉高压发病机制的进展。
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[The relation between acute embolism and thromboembolic pulmonary hypertension].[急性栓塞与血栓栓塞性肺动脉高压之间的关系]
Vnitr Lek. 1990 May;36(5):503-7.

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Association of Systemic Inflammatory Response Index with Disease Severity and Adverse Outcome in Chronic Thromboembolic Pulmonary Hypertension.全身炎症反应指数与慢性血栓栓塞性肺动脉高压疾病严重程度及不良预后的相关性
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Efficacy and influencing factors of thrombolytic therapy in patients with pulmonary embolism complicated y pulmonary arterial hypertension.肺栓塞合并肺动脉高压患者溶栓治疗的疗效及影响因素
Am J Transl Res. 2025 Apr 15;17(4):2654-2664. doi: 10.62347/RJDR4749. eCollection 2025.
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Advances and applications of biosensors in pulmonary hypertension.生物传感器在肺动脉高压中的进展与应用
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Chronic Thromboembolic Pulmonary Hypertension: A Review of the Multifaceted Pathobiology.慢性血栓栓塞性肺动脉高压:多方面病理生物学综述
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Preexisting Chronic Thromboembolic Pulmonary Hypertension in Acute Pulmonary Embolism? A Case Report and Discussion.急性肺栓塞中是否存在预先存在的慢性血栓栓塞性肺动脉高压?病例报告及讨论。
Hamostaseologie. 2024 Jun;44(3):193-196. doi: 10.1055/a-2173-7712. Epub 2023 Oct 30.
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The Cellular Landscape of Chronic Thromboembolic Pulmonary Hypertension Revealed by Single-Cell Sequencing: Therapeutic Implications?单细胞测序揭示慢性血栓栓塞性肺动脉高压的细胞图谱:对治疗有何启示?
Am J Respir Crit Care Med. 2023 May 15;207(10):1266-1268. doi: 10.1164/rccm.202302-0326ED.

本文引用的文献

1
Epigenetic Modification of the von Willebrand Factor Promoter Drives Platelet Aggregation on the Pulmonary Endothelium in Chronic Thromboembolic Pulmonary Hypertension.慢性血栓栓塞性肺动脉高压中血管性血友病因子启动子的表观遗传修饰驱动血小板在肺内皮聚集。
Am J Respir Crit Care Med. 2022 Apr 1;205(7):806-818. doi: 10.1164/rccm.202109-2075OC.
2
Neutrophil Extracellular Traps as Prognostic Markers in COVID-19: A Welcome Piece to the Puzzle.中性粒细胞胞外诱捕网作为COVID-19的预后标志物:拼图中受欢迎的一块。
Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):995-998. doi: 10.1161/ATVBAHA.120.315633. Epub 2021 Jan 27.
3
Neutrophil extracellular traps promote fibrous vascular occlusions in chronic thrombosis.中性粒细胞胞外诱捕网促进慢性血栓形成中的纤维血管闭塞。
Blood. 2021 Feb 25;137(8):1104-1116. doi: 10.1182/blood.2020005861.
4
The distinctive structure and composition of arterial and venous thrombi and pulmonary emboli.动脉和静脉血栓及肺栓塞的独特结构和组成。
Sci Rep. 2020 Mar 20;10(1):5112. doi: 10.1038/s41598-020-59526-x.
5
Klippel-Trenaunay syndrome as a rare cause of chronic thromboemboembolic pulmonary hypertension.克莱佩尔-特伦纳伊恩综合征作为慢性血栓栓塞性肺动脉高压的罕见病因。
Respir Med Res. 2019 Nov;76:48-53. doi: 10.1016/j.resmer.2019.06.002. Epub 2019 Jul 9.
6
Cell Type-Specific Roles of NF-κB Linking Inflammation and Thrombosis.NF-κB 在炎症与血栓形成中的细胞类型特异性作用。
Front Immunol. 2019 Feb 4;10:85. doi: 10.3389/fimmu.2019.00085. eCollection 2019.
7
Incidence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a contemporary view of the published literature.急性肺栓塞后慢性血栓栓塞性肺动脉高压的发生率:已发表文献的当代观点。
Eur Respir J. 2017 Feb 23;49(2). doi: 10.1183/13993003.01792-2016. Print 2017 Feb.
8
Platelets are highly activated in patients of chronic thromboembolic pulmonary hypertension.在慢性血栓栓塞性肺动脉高压患者中,血小板被高度激活。
Arterioscler Thromb Vasc Biol. 2014 Nov;34(11):2486-94. doi: 10.1161/ATVBAHA.114.304404. Epub 2014 Aug 28.
9
Update on chronic thromboembolic pulmonary hypertension.慢性血栓栓塞性肺动脉高压的最新进展。
Circulation. 2014 Aug 5;130(6):508-18. doi: 10.1161/CIRCULATIONAHA.114.009309.
10
Factors associated with diagnosis and operability of chronic thromboembolic pulmonary hypertension. A case-control study.与慢性血栓栓塞性肺动脉高压的诊断和可操作性相关的因素。一项病例对照研究。
Thromb Haemost. 2013 Jul;110(1):83-91. doi: 10.1160/TH13-02-0097. Epub 2013 May 16.

More Evidence for Inflammatory Thrombosis in Chronic Thromboembolic Pulmonary Hypertension: Is the Embolic Hypothesis Losing Ground?

作者信息

Sharma Smriti, Lang Irene M

机构信息

Department of Internal Medicine II (Cardiology) Medical University of Vienna Vienna, Austria.

出版信息

Am J Respir Crit Care Med. 2022 Apr 1;205(7):745-746. doi: 10.1164/rccm.202201-0001ED.

DOI:10.1164/rccm.202201-0001ED
PMID:35133253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9836223/
Abstract
摘要